Expression of AC133 Antigen and CD34 on ALL and AML
Leukemia . | AC133 . | CD34 . |
---|---|---|
1. T-ALL | Dim | + |
2. T-ALL | — | + |
3. C-ALL | — | + |
4. C-ALL | — | + |
5. C-ALL | Dim | + |
6. C-ALL | Bright | − |
7. C-ALL | — | − |
8. C-ALL | Dim | + |
9. Pro-B ALL | Bright | + |
10. AML M1/M2 | — | − |
11. AML M1/M2 | — | + |
12. AML M1/M2 | Dim | + |
13. AML M1/M2 | Bright | + |
14. AML M1/M2 | Dim | + |
15. AML M1/M2 | Dim | + |
16. AML M1/M2 | Bright | + |
17. AML M1/M2 | Dim | + |
18. AML M1/M2 | Bright | + |
19. AML M1/M2 | Bright | + |
20. AML M1/M2 | Dim | + |
21. AML M1/M2 | Dim | + |
22. AML M4/M5 | Dim | + |
23. AML M4/M5 | Dim | + |
24. AML M4/M5 | Dim | + |
25. AML M4/M5 | Dim | + |
26. AML M4/M5 | — | + |
27. AML M4/M5 | Bright | + |
28. AML M4/M5 | Dim | − |
29. AML M4/M5 | Dim | − |
30. AML M4/M5 | Dim | + |
31. AML M4/M5 | Dim | − |
32. AML M4/M5 | Bright | − |
Leukemia . | AC133 . | CD34 . |
---|---|---|
1. T-ALL | Dim | + |
2. T-ALL | — | + |
3. C-ALL | — | + |
4. C-ALL | — | + |
5. C-ALL | Dim | + |
6. C-ALL | Bright | − |
7. C-ALL | — | − |
8. C-ALL | Dim | + |
9. Pro-B ALL | Bright | + |
10. AML M1/M2 | — | − |
11. AML M1/M2 | — | + |
12. AML M1/M2 | Dim | + |
13. AML M1/M2 | Bright | + |
14. AML M1/M2 | Dim | + |
15. AML M1/M2 | Dim | + |
16. AML M1/M2 | Bright | + |
17. AML M1/M2 | Dim | + |
18. AML M1/M2 | Bright | + |
19. AML M1/M2 | Bright | + |
20. AML M1/M2 | Dim | + |
21. AML M1/M2 | Dim | + |
22. AML M4/M5 | Dim | + |
23. AML M4/M5 | Dim | + |
24. AML M4/M5 | Dim | + |
25. AML M4/M5 | Dim | + |
26. AML M4/M5 | — | + |
27. AML M4/M5 | Bright | + |
28. AML M4/M5 | Dim | − |
29. AML M4/M5 | Dim | − |
30. AML M4/M5 | Dim | + |
31. AML M4/M5 | Dim | − |
32. AML M4/M5 | Bright | − |
Bone marrow samples obtained after informed consent from patients with acute leukemia were stained with anti-CD34-FITC and AC133-PE and were analyzed by multiparameter flow cytometry. Leukemic blasts expressing AC133 antigen were subdivided into AC133dim (log fluorescence intensity between the first and the second decade) and AC133bright cells (log fluorescence intensity between the second and the third decade).