Pretreatment Patient Characteristics
Patient No. . | Age/Sex (yrs) . | Pretreatment Disease Duration (mos) . | Pathologic Diagnosis16 . | Prior Therapy . | Stage at Start of Cladribine . | Sites of Disease Involvement . |
---|---|---|---|---|---|---|
1 | 33/F | 204 | Presumptive | Prednisone, vinblastine, azathioprine, VP-16, methotrexate Radiation | I | Skin, external auditory canals, mouth, vagina, diabetes insipidus |
2 | 57/M | 7 | Definitive | Prednisone | II | Skin, neutropenia |
3 | 20/M | 176 | Presumptive | Prednisone, vinblastine, suppressin A (experimental), VP-16 C5 vertebrectomy | I | Bone (vertebrae, orbits, skull, sternum, ribs and pelvis) |
4 | 50/M | 21 | Presumptive | Prednisone Radiation Surgical debridement | I | Bone (mandible and ribs), gingiva, tooth loss, lung |
5 | 42/F | 133 | Diagnosis | Prednisone, vinblastine Radiation Bowel resection, partial hepatic resection | I | Skin, mouth, vagina, colon, diabetes insipidus |
6 | 35/M | 99 | Diagnosis | Topical nitrogen, mustard, VP-16 Electron beam radiation | I | Skin, soft tissue, diabetes Insipidus, pulmonary |
7 | 72/M | 34 | Definitive | Prednisone, cyclophosphamide Radiation | I | Skin |
8 | 47/M | 114 | Definitive | Radiation | II | Bone (mandible and maxilla), lung, edentulous |
9 | 37/M | 22 | Diagnosis | Prednisone, vinblastine Radiation Pericardiectomy | III | Bone (mandible, radius and ribs), soft tissue, lung, lymphadenopathy, ascites, diabetes insipidus |
10 | 68/F | 64 | Diagnosis | Vinblastine, methotrexate, 6-thioguanine Radiation | I | Skin, mouth, vagina, anemia |
11 | 34/M | 146 | Definitive | Vinblastine, vincristine, interferon, methotrexate, VP-16, prednisone Radiation | II | Bone (skull, hips, vertebrae, clavicle, tibia and ribs), lung |
12 | 46/F | 253 | Definitive | Vinblastine, methotrexate, isotretinoin, interferon Radiation | I | Skin |
13 | 19/F | 6 | Presumptive | None | II | Bone (skull, femur, fibula and pelvis), lung, lymphadenopathy |
Patient No. . | Age/Sex (yrs) . | Pretreatment Disease Duration (mos) . | Pathologic Diagnosis16 . | Prior Therapy . | Stage at Start of Cladribine . | Sites of Disease Involvement . |
---|---|---|---|---|---|---|
1 | 33/F | 204 | Presumptive | Prednisone, vinblastine, azathioprine, VP-16, methotrexate Radiation | I | Skin, external auditory canals, mouth, vagina, diabetes insipidus |
2 | 57/M | 7 | Definitive | Prednisone | II | Skin, neutropenia |
3 | 20/M | 176 | Presumptive | Prednisone, vinblastine, suppressin A (experimental), VP-16 C5 vertebrectomy | I | Bone (vertebrae, orbits, skull, sternum, ribs and pelvis) |
4 | 50/M | 21 | Presumptive | Prednisone Radiation Surgical debridement | I | Bone (mandible and ribs), gingiva, tooth loss, lung |
5 | 42/F | 133 | Diagnosis | Prednisone, vinblastine Radiation Bowel resection, partial hepatic resection | I | Skin, mouth, vagina, colon, diabetes insipidus |
6 | 35/M | 99 | Diagnosis | Topical nitrogen, mustard, VP-16 Electron beam radiation | I | Skin, soft tissue, diabetes Insipidus, pulmonary |
7 | 72/M | 34 | Definitive | Prednisone, cyclophosphamide Radiation | I | Skin |
8 | 47/M | 114 | Definitive | Radiation | II | Bone (mandible and maxilla), lung, edentulous |
9 | 37/M | 22 | Diagnosis | Prednisone, vinblastine Radiation Pericardiectomy | III | Bone (mandible, radius and ribs), soft tissue, lung, lymphadenopathy, ascites, diabetes insipidus |
10 | 68/F | 64 | Diagnosis | Vinblastine, methotrexate, 6-thioguanine Radiation | I | Skin, mouth, vagina, anemia |
11 | 34/M | 146 | Definitive | Vinblastine, vincristine, interferon, methotrexate, VP-16, prednisone Radiation | II | Bone (skull, hips, vertebrae, clavicle, tibia and ribs), lung |
12 | 46/F | 253 | Definitive | Vinblastine, methotrexate, isotretinoin, interferon Radiation | I | Skin |
13 | 19/F | 6 | Presumptive | None | II | Bone (skull, femur, fibula and pelvis), lung, lymphadenopathy |