Patient Characteristics by Randomization
| . | TAD-TAD . | TAD-HAM . |
|---|---|---|
| No. of patients | 360 | 365 |
| Median age (range) | 44 (16-60) | 44 (16-60) |
| Female/Male | 193/167 | 196/169 |
| Median WBC/μL ×103 (range) | 17.2 (0.1-405) | 21.0 (0.5-331) |
| Median LDH (U/L; range) | 400 (90-3,600) | 443 (102-2,868) |
| FAB subtypes (% of patients) | ||
| M0 | 0 | 1 |
| M1 | 16 | 17 |
| M2 | 26 | 33 |
| M3 | 7 | 5 |
| M4 total (M4Eo) | 34 (7) | 29 (6) |
| M5 | 12 | 11 |
| M6 | 4 | 3 |
| M7 | 1 | 1 |
| Cytogenetics (no. available) | 172 | 171 |
| Different karyotypes in percentages | ||
| t (15; 17) | 6 | 5 |
| t (8;21) | 6 | 10 |
| inv (16) | 8 | 9 |
| −5/5q− | 3 | 1 |
| −7/7q− | 4 | 3 |
| Abnormal 11q23 | 1 | 4 |
| Complex karyotype | 8 | 4 |
| Other abnormal karyotype | 11 | 18 |
| Normal karyotype | 53 | 46 |
| Cytogenetics (no. not available) | 188 | 194 |
| . | TAD-TAD . | TAD-HAM . |
|---|---|---|
| No. of patients | 360 | 365 |
| Median age (range) | 44 (16-60) | 44 (16-60) |
| Female/Male | 193/167 | 196/169 |
| Median WBC/μL ×103 (range) | 17.2 (0.1-405) | 21.0 (0.5-331) |
| Median LDH (U/L; range) | 400 (90-3,600) | 443 (102-2,868) |
| FAB subtypes (% of patients) | ||
| M0 | 0 | 1 |
| M1 | 16 | 17 |
| M2 | 26 | 33 |
| M3 | 7 | 5 |
| M4 total (M4Eo) | 34 (7) | 29 (6) |
| M5 | 12 | 11 |
| M6 | 4 | 3 |
| M7 | 1 | 1 |
| Cytogenetics (no. available) | 172 | 171 |
| Different karyotypes in percentages | ||
| t (15; 17) | 6 | 5 |
| t (8;21) | 6 | 10 |
| inv (16) | 8 | 9 |
| −5/5q− | 3 | 1 |
| −7/7q− | 4 | 3 |
| Abnormal 11q23 | 1 | 4 |
| Complex karyotype | 8 | 4 |
| Other abnormal karyotype | 11 | 18 |
| Normal karyotype | 53 | 46 |
| Cytogenetics (no. not available) | 188 | 194 |