Effect of AG957 on CML and Normal LTC-IC
| AG957 (μmol/L) . | CML . | Normal . |
|---|---|---|
| 0 | 0 | 0 |
| 1 | −18 ± 15 | 1 ± 7 |
| 5 | 21 ± 8 | 10 ± 4 |
| 10 | 22 ± 17 | 16 ± 14 |
| 50 | 76 ± 15 | 19 ± 10 |
| 100 | 100 | 29 ± 12 |
| AG957 (μmol/L) . | CML . | Normal . |
|---|---|---|
| 0 | 0 | 0 |
| 1 | −18 ± 15 | 1 ± 7 |
| 5 | 21 ± 8 | 10 ± 4 |
| 10 | 22 ± 17 | 16 ± 14 |
| 50 | 76 ± 15 | 19 ± 10 |
| 100 | 100 | 29 ± 12 |
Results are the percentage of inhibition and are expressed as the mean (±SEM) values of five and three separate experiments for CML and normal, respectively.