Phenotypic Investigation of the Affected Family
| Relationship . | Age (yrs) . | AT Activity (%) . | AT Antigen (%) . | Thrombosis . | |
|---|---|---|---|---|---|
| Anti-IIa . | Anti-Xa . | ||||
| Proband | 27 | 67 (6) | 66 (5) | 68 (3) | None |
| Mother | 50 | 94 | ND | 85 | None |
| Father | 60 | 72 (1) | 68 (6) | 67 (1) | MI, 58 yrs |
| Sister | 26 | 73 (1) | 63 (8) | 67 (2) | None |
| Normal range | 80-120 | 80-120 | 80-120 | ||
| Relationship . | Age (yrs) . | AT Activity (%) . | AT Antigen (%) . | Thrombosis . | |
|---|---|---|---|---|---|
| Anti-IIa . | Anti-Xa . | ||||
| Proband | 27 | 67 (6) | 66 (5) | 68 (3) | None |
| Mother | 50 | 94 | ND | 85 | None |
| Father | 60 | 72 (1) | 68 (6) | 67 (1) | MI, 58 yrs |
| Sister | 26 | 73 (1) | 63 (8) | 67 (2) | None |
| Normal range | 80-120 | 80-120 | 80-120 | ||
Mean (SD) of levels measured on three occasions over a 4-year period, except in the case of the mother where a single sample only was available.
Abbreviations: MI, myocardial infarction; ND, not done.