Effect of Jaspamide on Phagocytosis of C albicans by HL-60 Cells and Monocytes
| Treatment . | HL-60 Cells . | Monocytes . | ||
|---|---|---|---|---|
| (%) Cells . | Phagocytosis Index . | (%) Cells . | Phagocytosis Index . | |
| Nil | 6.3 ± 2.2 | 0.17 ± 0.02 | 86.3 ± 4.7 | 3.0 ± 0.2 |
| DMSO (0.01%) | 6.6 ± 0.6 | 0.17 ± 0.02 | 80.2 ± 7.0 | 2.5 ± 0.55 |
| Jaspamide 10−7 mol/L | 9.3 ± 1.3 | 0.22 ± 0.02 | 87.5 ± 4.0 | 2.4 ± 0.55 |
| Treatment . | HL-60 Cells . | Monocytes . | ||
|---|---|---|---|---|
| (%) Cells . | Phagocytosis Index . | (%) Cells . | Phagocytosis Index . | |
| Nil | 6.3 ± 2.2 | 0.17 ± 0.02 | 86.3 ± 4.7 | 3.0 ± 0.2 |
| DMSO (0.01%) | 6.6 ± 0.6 | 0.17 ± 0.02 | 80.2 ± 7.0 | 2.5 ± 0.55 |
| Jaspamide 10−7 mol/L | 9.3 ± 1.3 | 0.22 ± 0.02 | 87.5 ± 4.0 | 2.4 ± 0.55 |
HL-60 cells and monocytes were incubated with C albicansfor 60 minutes and tested for percentage of phagocytosing cells and phagocytosis index. Values represent mean ± SE of 3 experiments.