Effect of Jaspamide on the Expression of CD16 and CD14B Antigens by HL-60 Cells
| Antigen . | Positive Cells (%) . | Delta % . | Reactivity . | ||
|---|---|---|---|---|---|
| DMSO Treated . | Jaspamide Treated . | Monocytes . | Granulocytes . | ||
| CD16 (306) | 28.5 | 81.5 | 53.0 | + | +++ |
| CD14B (253) | 20.7 | 47.3 | 26.6 | +++ | − |
| Antigen . | Positive Cells (%) . | Delta % . | Reactivity . | ||
|---|---|---|---|---|---|
| DMSO Treated . | Jaspamide Treated . | Monocytes . | Granulocytes . | ||
| CD16 (306) | 28.5 | 81.5 | 53.0 | + | +++ |
| CD14B (253) | 20.7 | 47.3 | 26.6 | +++ | − |
Cells were incubated for 48 hours with 10−7 mol/L jaspamide or 0.01% DMSO. FACS analysis was performed as described in Materials and Methods. Similar results were observed in three additional experiments.