Correlation Between Activation and Expression of ERK
ERK Activation . | No. . | ERK Hyperexpression . | |
---|---|---|---|
Positive3-151 . | Negative . | ||
Positive3-150 | 19 | 12 | 7 |
Negative | 7 | 2 | 5 |
Total | 26 | 14 | 12 |
ERK Activation . | No. . | ERK Hyperexpression . | |
---|---|---|---|
Positive3-151 . | Negative . | ||
Positive3-150 | 19 | 12 | 7 |
Negative | 7 | 2 | 5 |
Total | 26 | 14 | 12 |
P = .19.
Defined as positive when the value of the ERK2 phosphorylation divided by the α-tubulin expression was greater than one third the value of K562 cell by immunoblot analysis.
Defined as positive when the value of the total ERK expression divided by the α-tubulin expression as twofold the mean value of normal BM samples by immunoblot analysis.14