Genes Potentially Regulated by RAR in Myeloid Differentiation
| Class of Genes . | Examples/References . |
|---|---|
| Regulators of the cell cycle | Cyclins, cyclin-dependent kinases and CDK inhibitors129,130 550 |
| Cell surface adhesion molecules | CD11b, CD1871 551-554 |
| Intrinsic host defense systems and extrinsic cytokines | Monocyte chemo-attractant factor, interleukins142 555 |
| Neutrophil granule proteins | Defensin, secondary granule proteins, leukocyte alkaline phosphatase, lactoferrin93 556-559 |
| Colony-stimulating factors | IL-1β, IL-8, G-CSF329,560 561 |
| Colony-stimulating factor receptors | M-CSFR, G-CSFR562 563 |
| Regulators of apoptosis and terminal cell division | Transglutaminase II,71 137 bcl2564 |
| Structural proteins, enzymes, chromatin components | 26,38,136 565 |
| Clotting factors | Thrombomodulin, tissue factor, urokinase, tissue plasminogen activator and its inhibitors566-568 |
| Transcription factors | RARs,32,38,94STATs,120 Hox genes97 98 |
| Class of Genes . | Examples/References . |
|---|---|
| Regulators of the cell cycle | Cyclins, cyclin-dependent kinases and CDK inhibitors129,130 550 |
| Cell surface adhesion molecules | CD11b, CD1871 551-554 |
| Intrinsic host defense systems and extrinsic cytokines | Monocyte chemo-attractant factor, interleukins142 555 |
| Neutrophil granule proteins | Defensin, secondary granule proteins, leukocyte alkaline phosphatase, lactoferrin93 556-559 |
| Colony-stimulating factors | IL-1β, IL-8, G-CSF329,560 561 |
| Colony-stimulating factor receptors | M-CSFR, G-CSFR562 563 |
| Regulators of apoptosis and terminal cell division | Transglutaminase II,71 137 bcl2564 |
| Structural proteins, enzymes, chromatin components | 26,38,136 565 |
| Clotting factors | Thrombomodulin, tissue factor, urokinase, tissue plasminogen activator and its inhibitors566-568 |
| Transcription factors | RARs,32,38,94STATs,120 Hox genes97 98 |