Clinical and Laboratory Characteristics of Liver Cirrhotic Patients According to Child-Pugh’s Classification
| Variable . | Grade A (n = 6) . | A v B PValue . | Grade B (n = 20) . | B v C P Value . | Grade C (n = 4) . | A v C P Value . |
|---|---|---|---|---|---|---|
| Age (yr) NS | 58 (34-74) | NS | 58 (44-79) | NS | 63 (56-69) | NS |
| No. of men (%) NS | 4 (67) | NS | 13 (65) | NS | 2 (50) | NS |
| Serum albumin (g/dL) H = 10.1, P = .0065 | 4.15 (3.7-4.7) | .005 | 2.95 (2.3-4.8) | NS | 2.55 (2.2-3.5) | .010 |
| Prothrombin activity (%) H = 11.8, P = .0027 | 87 (70-97) | .012 | 69 (37-92) | .020 | 47 (40-65) | .010 |
| TF antigen (pg/2 × 105 monocytes) H = 14.0, P = .0009 | 7.5 (5-56.4) | .005 | 41.55 (8-76.8) | .008 | 89.9 (58-101.8) | .010 |
| TF activity (U/2 × 105 monocytes) H = 11.4, P = .0034 | 2.5 (0-25) | .016 | 17.5 (0-35) | .015 | 40.5 (20-50) | .018 |
| Isoprostane-F2α-III (pg/mg creatinine) H = 10.4, P = .0055 | 108 (92-285) | .024 | 263.5 (44-432) | .02 | 600 (260-812) | .019 |
| F1 + 2 (nmol/L) H = 10.2, P = .0062 | 0.95 (0.6-2.15) | .026 | 1.82 (0.75-2.4) | .022 | 3.05 (1.8-3.3) | .019 |
| Endotoxemia (pg/mL) H = 16.9,P = .0002 | 5.4 (3.1-9.5) | .0006 | 21.83 (5.8-53.3) | .009 | 56.7 (23.4-62.0) | .010 |
| Variable . | Grade A (n = 6) . | A v B PValue . | Grade B (n = 20) . | B v C P Value . | Grade C (n = 4) . | A v C P Value . |
|---|---|---|---|---|---|---|
| Age (yr) NS | 58 (34-74) | NS | 58 (44-79) | NS | 63 (56-69) | NS |
| No. of men (%) NS | 4 (67) | NS | 13 (65) | NS | 2 (50) | NS |
| Serum albumin (g/dL) H = 10.1, P = .0065 | 4.15 (3.7-4.7) | .005 | 2.95 (2.3-4.8) | NS | 2.55 (2.2-3.5) | .010 |
| Prothrombin activity (%) H = 11.8, P = .0027 | 87 (70-97) | .012 | 69 (37-92) | .020 | 47 (40-65) | .010 |
| TF antigen (pg/2 × 105 monocytes) H = 14.0, P = .0009 | 7.5 (5-56.4) | .005 | 41.55 (8-76.8) | .008 | 89.9 (58-101.8) | .010 |
| TF activity (U/2 × 105 monocytes) H = 11.4, P = .0034 | 2.5 (0-25) | .016 | 17.5 (0-35) | .015 | 40.5 (20-50) | .018 |
| Isoprostane-F2α-III (pg/mg creatinine) H = 10.4, P = .0055 | 108 (92-285) | .024 | 263.5 (44-432) | .02 | 600 (260-812) | .019 |
| F1 + 2 (nmol/L) H = 10.2, P = .0062 | 0.95 (0.6-2.15) | .026 | 1.82 (0.75-2.4) | .022 | 3.05 (1.8-3.3) | .019 |
| Endotoxemia (pg/mL) H = 16.9,P = .0002 | 5.4 (3.1-9.5) | .0006 | 21.83 (5.8-53.3) | .009 | 56.7 (23.4-62.0) | .010 |
Data are expressed as the median, with the range in parentheses.
Abbreviations: H, Kruskal-Wallis test; TF, tissue factor; F1 + 2, human prothrombin fragment F1 + 2; NS, not significant.