Table 3.

Summary of Transplanted MNC, CFU-GM, and Hematologic Recovery

No. MNC (×107/kg)CFU-GM (×104/kg) Days to Neutrophils >500/μL Days to Platelets >5 × 104/μL
Transduced UntransducedTotal Transduced Untransduced Total
1  — 7.8  7.8  —  5.9  5.9  35  28  
2  4.0 3.0  7.0  1.5  2.5  4.0  25  28 
    (6.7%)3-150  (2.5%)3-151 
3  5.7  2.8 8.5  2.5  3.3  5.8  39  39 
    (5.9%)3-150  (2.1%)3-151 
4  6.9  1.1 8.0  8.1  4.4  12.5  33  33 
    (13.7%)3-150  (8.9%)3-151 
No. MNC (×107/kg)CFU-GM (×104/kg) Days to Neutrophils >500/μL Days to Platelets >5 × 104/μL
Transduced UntransducedTotal Transduced Untransduced Total
1  — 7.8  7.8  —  5.9  5.9  35  28  
2  4.0 3.0  7.0  1.5  2.5  4.0  25  28 
    (6.7%)3-150  (2.5%)3-151 
3  5.7  2.8 8.5  2.5  3.3  5.8  39  39 
    (5.9%)3-150  (2.1%)3-151 
4  6.9  1.1 8.0  8.1  4.4  12.5  33  33 
    (13.7%)3-150  (8.9%)3-151 

Animal No. 1 was transplanted only with untransduced PBPC as a control.

F3-150

Transduction efficiency (percentage of VCR resistant colonies).

F3-151

Transduction efficiency was calculated from the numbers of transduced and untransduced CFU-GM.

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