Characteristics of the 55 Patients Receiving an Allogeneic Stem Cell Transplantation for AMM
| . | Marrow Fibrosis . | Overall Group n = 55 . | |
|---|---|---|---|
| Grade I-II n = 28 . | Grade III n = 27 . | ||
| Age at diagnosis | |||
| >40 yr | 13 | 8 | 21 |
| Hemoglobin ≤100 g/L at diagnosis | 8 | 9 | 17 |
| Blasts in peripheral blood at diagnosis | 9 | 11 | 20 |
| Intermediate- + high-risk scores at diagnosis* | 10 | 11 | 21 |
| Cytogenetic abnormalities before transplant | 8 | 5 | 13 |
| Treatments before transplant | |||
| None | 8 | 5 | 13 |
| Chemotherapy | 13 | 15 | 28 |
| Other treatments | 8 | 12 | 20 |
| Splenectomy | 12 | 15 | 27 |
| Transfusions before transplant | |||
| RBC transfusions | 16 | 20 | 36 |
| 10 or more RBC units transfused | 10 | 12 | 22 |
| Platelet transfusions | 6 | 5 | 11 |
| Age at transplant (yr) | |||
| <40 | 10 | 15 | 25 |
| ≥40 | 18 | 12 | 30 |
| ≥44 | 15† | 8 | 23 |
| ≥48 | 8 | 3 | 11 |
| Time from diagnosis to transplant (mo) | |||
| <24 | 19‡ | 12 | 31 |
| ≥24 | 9 | 15 | 24 |
| ≥48 | 6 | 9 | 15 |
| Hemoglobin ≤100 g/L at transplant | 15 | 20 | 35 |
| Blasts in peripheral blood at transplant | 6 | 11 | 17 |
| Intermediate- + high-risk scores at transplant* | 19 | 23 | 42 |
| . | Marrow Fibrosis . | Overall Group n = 55 . | |
|---|---|---|---|
| Grade I-II n = 28 . | Grade III n = 27 . | ||
| Age at diagnosis | |||
| >40 yr | 13 | 8 | 21 |
| Hemoglobin ≤100 g/L at diagnosis | 8 | 9 | 17 |
| Blasts in peripheral blood at diagnosis | 9 | 11 | 20 |
| Intermediate- + high-risk scores at diagnosis* | 10 | 11 | 21 |
| Cytogenetic abnormalities before transplant | 8 | 5 | 13 |
| Treatments before transplant | |||
| None | 8 | 5 | 13 |
| Chemotherapy | 13 | 15 | 28 |
| Other treatments | 8 | 12 | 20 |
| Splenectomy | 12 | 15 | 27 |
| Transfusions before transplant | |||
| RBC transfusions | 16 | 20 | 36 |
| 10 or more RBC units transfused | 10 | 12 | 22 |
| Platelet transfusions | 6 | 5 | 11 |
| Age at transplant (yr) | |||
| <40 | 10 | 15 | 25 |
| ≥40 | 18 | 12 | 30 |
| ≥44 | 15† | 8 | 23 |
| ≥48 | 8 | 3 | 11 |
| Time from diagnosis to transplant (mo) | |||
| <24 | 19‡ | 12 | 31 |
| ≥24 | 9 | 15 | 24 |
| ≥48 | 6 | 9 | 15 |
| Hemoglobin ≤100 g/L at transplant | 15 | 20 | 35 |
| Blasts in peripheral blood at transplant | 6 | 11 | 17 |
| Intermediate- + high-risk scores at transplant* | 19 | 23 | 42 |