Table 6. CFU-GM, CFU-GEMM, CFU-MK and... | American Society of Hematology

Table 6.

CFU-GM, CFU-GEMM, CFU-MK and BFU-E Growth by rhTPO Dose in Patients Mobilized by rhTPO in Combination With G-CSF

rhTPO (μg/kg)	CFU-GM^6-150		CFU-GEMM^6-150		CFU-MK^6-150		BFU-E^6-150
rhTPO (μg/kg)	Median	Range	Median	Range	Median	Range	Median	Range
Arm A
0.6 × 1	0.9	0.7-2.5	0.11	0.07-0.11	0.9	0.9-1.2	1.6	1.2-3.0
1.2 × 1	2.5	0.9-6.5	0.22	0.09-0.68	0.8	0.3-2.0	2.9	1.5-8.2
2.4 × 1	1.2	0.7-1.6	0.12	0.03-0.26	0.6	0.4-1.6	2.2	1.3-3.5
Arm B
0.3 × 3	2.2	0.6-2.8	0.26	0.05-0.42	0.9	0.4-1.6	3.0	1.1-3.7
0.6 × 3	2.9	0.8-10.1	0.67	0.05-1.04	1.8	0.6-3.5	4.7	1.7-10.3
Arm C
0.6 × 2	2.5	1.1-5.2	0.58	0.12-1.46	0.8	0.6-2.6	4.3	2.3-5.0

rhTPO (μg/kg)	CFU-GM^6-150		CFU-GEMM^6-150		CFU-MK^6-150		BFU-E^6-150
rhTPO (μg/kg)	Median	Range	Median	Range	Median	Range	Median	Range
Arm A
0.6 × 1	0.9	0.7-2.5	0.11	0.07-0.11	0.9	0.9-1.2	1.6	1.2-3.0
1.2 × 1	2.5	0.9-6.5	0.22	0.09-0.68	0.8	0.3-2.0	2.9	1.5-8.2
2.4 × 1	1.2	0.7-1.6	0.12	0.03-0.26	0.6	0.4-1.6	2.2	1.3-3.5
Arm B
0.3 × 3	2.2	0.6-2.8	0.26	0.05-0.42	0.9	0.4-1.6	3.0	1.1-3.7
0.6 × 3	2.9	0.8-10.1	0.67	0.05-1.04	1.8	0.6-3.5	4.7	1.7-10.3
Arm C
0.6 × 2	2.5	1.1-5.2	0.58	0.12-1.46	0.8	0.6-2.6	4.3	2.3-5.0

Units are expressed × 10⁶/kg.