Table 2. PBPC Yield and Transfusion... | American Society of Hematology

Table 2.

PBPC Yield and Transfusion Requirements

Variable	Prior Radiation	rhTPO Group			Control Group			P Value^*
Variable	Prior Radiation	Median	Range	N	Median	Range	N	P Value^*
No. of aphereses to procure	No	1	1-3	22	2	1-5+	14	.0005
>3 × 10⁶CD34⁺ cells/kg	Yes	1	1-2	4	3	3-4+	6	.001
	All patients	1	1-3	26	3	1-5+	20	<.0001
CD34⁺ × 10⁶/kg/first apheresis	No	3.6	1.3-18	22	1.3	0.3-4.2	14	.0005
	Yes	5.1	2.4-15	4	0.7	0.6-0.9	4	.014
	All patients	4.1	1.3-17.6	26	0.8	0.3-4.2	20	.0003
No. of RBC transfusions^†	No	3	2-7	21	4.5	2-10	14	.07
	Yes	3.5	3-4	2	4	3-8	6	.37
	All patients	3	2-7	23	4	2-10	20	.02
No. of platelet transfusions^†	No	4	0-10	21	5	2-19	14	.09
	Yes	3	2-4	2	6.5	3-11	6	.2
	All patients	4	0-10	23	5	2-19	20	.02

Variable	Prior Radiation	rhTPO Group			Control Group			P Value^*
Variable	Prior Radiation	Median	Range	N	Median	Range	N	P Value^*
No. of aphereses to procure	No	1	1-3	22	2	1-5+	14	.0005
>3 × 10⁶CD34⁺ cells/kg	Yes	1	1-2	4	3	3-4+	6	.001
	All patients	1	1-3	26	3	1-5+	20	<.0001
CD34⁺ × 10⁶/kg/first apheresis	No	3.6	1.3-18	22	1.3	0.3-4.2	14	.0005
	Yes	5.1	2.4-15	4	0.7	0.6-0.9	4	.014
	All patients	4.1	1.3-17.6	26	0.8	0.3-4.2	20	.0003
No. of RBC transfusions^†	No	3	2-7	21	4.5	2-10	14	.07
	Yes	3.5	3-4	2	4	3-8	6	.37
	All patients	3	2-7	23	4	2-10	20	.02
No. of platelet transfusions^†	No	4	0-10	21	5	2-19	14	.09
	Yes	3	2-4	2	6.5	3-11	6	.2
	All patients	4	0-10	23	5	2-19	20	.02

Comparisons between the rhTPO v control groups were performed using the Wilcoxon rank-sum test. F test, adjusting for prior radiation, was used to combine strata in the overall analysis.

†

Transfusion requirements were evaluated in 23 assessable patients.

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