Current Classification of Plasminogen (Plg) Deficiency
| . | Immunoreactive Plg Antigen in Plasma (mg/dL) . | Total Functional Plg Activity in Plasma (%) . | Known Mutations in the Plasminogen Gene . | References . |
|---|---|---|---|---|
| Type I | Decreased | Decreased | Arg216 → His, Trp597 → Stop, Trp597 → Cys | 16 |
| Glu460 → Stop | 17 | |||
| Ser572 → Pro, Ala675 → Thr | 22, 38 | |||
| del Lys212, Arg513 → His, Thr9 → Asn, Ex17 + 1del-g | This report | |||
| Leu128 → Pro, Lys19 → Glu | ||||
| Type II | Normal or slightly decreased | Decreased | Ala601 → Thr, Val355 → Phe, Asp676 → Asn Gly732 → Arg | 23, 42-46 54 |
| . | Immunoreactive Plg Antigen in Plasma (mg/dL) . | Total Functional Plg Activity in Plasma (%) . | Known Mutations in the Plasminogen Gene . | References . |
|---|---|---|---|---|
| Type I | Decreased | Decreased | Arg216 → His, Trp597 → Stop, Trp597 → Cys | 16 |
| Glu460 → Stop | 17 | |||
| Ser572 → Pro, Ala675 → Thr | 22, 38 | |||
| del Lys212, Arg513 → His, Thr9 → Asn, Ex17 + 1del-g | This report | |||
| Leu128 → Pro, Lys19 → Glu | ||||
| Type II | Normal or slightly decreased | Decreased | Ala601 → Thr, Val355 → Phe, Asp676 → Asn Gly732 → Arg | 23, 42-46 54 |