Table 2. Effect of the Addition of... | American Society of Hematology

Table 2.

Effect of the Addition of Anti-CD3 and Anti-HLA Class I MoAbs on the Cytolytic Activity of LB-Reactive TCC Against Autologous Pretransplant LB

TCC No.	Phenotype	% of Specific Lysis
TCC No.	Phenotype	Untreated	+Anti-CD3	+Anti-HLA Class I
6^*	TCR αβ⁺/CD8⁺	35	2	6
8^*	TCR αβ⁺/CD8⁺	68	9	8
13^*	TCR αβ⁺/CD8⁻/CD4⁻	26	32	28
15^*	TCR γδ⁺/CD8⁺	26	30	21
2^†	TCR αβ⁺/CD8⁺	58	26	8
7^†	TCR αβ⁺/CD8⁺	36	6	4
15^†	TCR γδ⁺/CD8⁺	15	12	17
18^†	TCR γδ⁺/CD8⁻/CD4⁻	35	30	25

TCC No.	Phenotype	% of Specific Lysis
TCC No.	Phenotype	Untreated	+Anti-CD3	+Anti-HLA Class I
6^*	TCR αβ⁺/CD8⁺	35	2	6
8^*	TCR αβ⁺/CD8⁺	68	9	8
13^*	TCR αβ⁺/CD8⁻/CD4⁻	26	32	28
15^*	TCR γδ⁺/CD8⁺	26	30	21
2^†	TCR αβ⁺/CD8⁺	58	26	8
7^†	TCR αβ⁺/CD8⁺	36	6	4
15^†	TCR γδ⁺/CD8⁺	15	12	17
18^†	TCR γδ⁺/CD8⁻/CD4⁻	35	30	25

Results are expressed as the percentage of specific lysis at an E:T ratio of 5:1.

TCC isolated from untreated cultures.

TCC isolated from IT-treated cultures.