Table 3.

Megakaryocyte Profile in the Spleen of Control and Thrombocytopenic Mice

CD-1 Mice W/B F1
Control (n = 5) Irradiated (n = 5)1 d RAMPS (n = 5) 5 d RAMPS (n = 6) Male (n = 6) Female Control (n = 3)
Megakaryocytes (per 10 hpf)  10.2 ± 1.4  0.5 ± 0.73-150 14.6 ± 2.8 29.8 ± 8.13-150,3-151 20.9 ± 4.63-152 6.32 ± 2.45 
CD-1 Mice W/B F1
Control (n = 5) Irradiated (n = 5)1 d RAMPS (n = 5) 5 d RAMPS (n = 6) Male (n = 6) Female Control (n = 3)
Megakaryocytes (per 10 hpf)  10.2 ± 1.4  0.5 ± 0.73-150 14.6 ± 2.8 29.8 ± 8.13-150,3-151 20.9 ± 4.63-152 6.32 ± 2.45 

Data were determined from histologic sections at 400× magnification with a minimum of 40 hpf counted per mouse (mean ± SD).

F3-150

P < .05 when compared with CD-1 control.

F3-151

P < .05 when compared with irradiated.

F3-152

P < .05 when compared with F1 female control.

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