Table 4. Patient and Tumor... | American Society of Hematology

Table 4.

Patient and Tumor Characteristics at Time of First Diagnosis of ALCL

	ALK Positive (N = 13)	ALK Negative		P Value^4-150
	ALK Positive (N = 13)	<15% Activated CTLs (N = 13)	≥15% Activated CTLs (N = 16)	P Value^4-150
Median age (range)	23 (2-69)	43 (18-74)	53 (13-82)	.032^4-151
Sex (male/female)	9/4	8/5	10/6	NS
Stage
I	5	2	2
II	6	4	2
III	1	3	5
IV	1	4	7	NS
B symptoms
No	8	6	6
Yes	5	7	10	NS
Extranodal sites
1	0	0	1
>1	1	3	4	NS
Elevated LDH	2	5	7	NS
IPI
Low	11	6	5
Low-intermediate	2	3	4
High-intermediate	0	2	3
High	0	2	4	NS
Complete remission	13	12	8	.002
Relapse	1	5	6	<.001
Cause of death
ALCL	0	3	13
Other	0	1	0	<.001

	ALK Positive (N = 13)	ALK Negative		P Value^4-150
	ALK Positive (N = 13)	<15% Activated CTLs (N = 13)	≥15% Activated CTLs (N = 16)	P Value^4-150
Median age (range)	23 (2-69)	43 (18-74)	53 (13-82)	.032^4-151
Sex (male/female)	9/4	8/5	10/6	NS
Stage
I	5	2	2
II	6	4	2
III	1	3	5
IV	1	4	7	NS
B symptoms
No	8	6	6
Yes	5	7	10	NS
Extranodal sites
1	0	0	1
>1	1	3	4	NS
Elevated LDH	2	5	7	NS
IPI
Low	11	6	5
Low-intermediate	2	3	4
High-intermediate	0	2	3
High	0	2	4	NS
Complete remission	13	12	8	.002
Relapse	1	5	6	<.001
Cause of death
ALCL	0	3	13
Other	0	1	0	<.001

Abbreviation: NS, not significant.

As determined by Pearson χ² test unless otherwise indicated.

As determined by the Kruskal-Wallis test.