Table 2. Survival Model Factor . Effect... | American Society of Hematology

Table 2.

Survival Model

Factor	Effect on Survival	P Value
Age	Worse with increasing age	<.001
Platelets	Survival improves as pretreatment platelet count increases from less than 5,000 to approximately 140,000, then worsens with further increase in platelets	<.001
Treated in PE	Favorable	<.001
PS 3, 4	Unfavorable	<.001
Treated as emergency	Unfavorable	.030
−5/−7^*,^†	Unfavorable	<.001
Other poor cytogenetics^‡	Unfavorable	.050

Factor	Effect on Survival	P Value
Age	Worse with increasing age	<.001
Platelets	Survival improves as pretreatment platelet count increases from less than 5,000 to approximately 140,000, then worsens with further increase in platelets	<.001
Treated in PE	Favorable	<.001
PS 3, 4	Unfavorable	<.001
Treated as emergency	Unfavorable	.030
−5/−7^*,^†	Unfavorable	<.001
Other poor cytogenetics^‡	Unfavorable	.050

Versus a normal karyotype or insufficient material for cytogenetic analysis.

−5/−7 refers to patients with clonal abnormalities involving −5, −7, del 5q−, or del 7q.

Other poor cytogenetics includes all cytogenetic abnormalities associated with AML/MDS, excluding inv(16), t(8;21), and −5/−7.