Allele Frequency of the S65C Substitution in Chromosomes Without the C282Y or H63D Mutations
| Genotype . | S65C/Neither C282Y nor H63D Allele . | ||||
|---|---|---|---|---|---|
| C282Y . | H63D . | HH . | Controls . | HH . | Controls . |
| +/− | −/− | 31 | 50 | 0.16 (5/31) | 0.02 (1/50) |
| −/− | +/− | 27 | 100 | 0.07 (2/27) | 0.03 (3/100) |
| −/− | −/− | 35 | 246 | 0.043 (3/70) | 0.024 (12/492) |
| P = .0078 | |||||
| Genotype . | S65C/Neither C282Y nor H63D Allele . | ||||
|---|---|---|---|---|---|
| C282Y . | H63D . | HH . | Controls . | HH . | Controls . |
| +/− | −/− | 31 | 50 | 0.16 (5/31) | 0.02 (1/50) |
| −/− | +/− | 27 | 100 | 0.07 (2/27) | 0.03 (3/100) |
| −/− | −/− | 35 | 246 | 0.043 (3/70) | 0.024 (12/492) |
| P = .0078 | |||||
+ and − indicate the presence and absence of mutations, respectively.