Table 1. FECH Allele Distribution in 39... | American Society of Hematology

Table 1.

FECH Allele Distribution in 39 Unrelated EPP Families

Polymorphisms	Alleles	Controls (n = 70)	EPP Patients (n = 39)	Normal Parents (n = 16)	Transmitter Parents (n = 22)
−251A/G	A	122	33	12	36
	G	18	45	20	8
			(49.00, <10⁻⁶)^*	(37.29, <10⁻⁶)	(0.78, NS)
IVS1 − 23C/T	C	119	34	11	37
	T	21	44	21	7
			(41.04, <10⁻⁶)	(36.7, <10⁻⁶)	(0.02, NS)
IVS2μsatAn_1-10	1	18	4	4	8
	2	6	0	0	0
	3	20	7	4	9
	4	1	0	0	0
	5	1	0	0	0
	6	1	1	0	0
	7	10	3	0	4
	8	3	0	0	1
	9	80	62	24	22
	10	0	1	0	0
			(11.01, <10⁻³)^†	(3.47, 0.06)	(0.69, NS)
798G/C	G	104	50	19	30
	C	36	28	13	14
			(2.5, NS)	(2.8, NS)	(0.63, NS)
1520C/T	C	120	52	21	38
	T	20	26	11	6
			(10.90, <10⁻³)	(7.11, <10⁻²)	(0.01, NS)

Polymorphisms	Alleles	Controls (n = 70)	EPP Patients (n = 39)	Normal Parents (n = 16)	Transmitter Parents (n = 22)
−251A/G	A	122	33	12	36
	G	18	45	20	8
			(49.00, <10⁻⁶)^*	(37.29, <10⁻⁶)	(0.78, NS)
IVS1 − 23C/T	C	119	34	11	37
	T	21	44	21	7
			(41.04, <10⁻⁶)	(36.7, <10⁻⁶)	(0.02, NS)
IVS2μsatAn_1-10	1	18	4	4	8
	2	6	0	0	0
	3	20	7	4	9
	4	1	0	0	0
	5	1	0	0	0
	6	1	1	0	0
	7	10	3	0	4
	8	3	0	0	1
	9	80	62	24	22
	10	0	1	0	0
			(11.01, <10⁻³)^†	(3.47, 0.06)	(0.69, NS)
798G/C	G	104	50	19	30
	C	36	28	13	14
			(2.5, NS)	(2.8, NS)	(0.63, NS)
1520C/T	C	120	52	21	38
	T	20	26	11	6
			(10.90, <10⁻³)	(7.11, <10⁻²)	(0.01, NS)

Abbreviation: NS, not significant.

(χ² (df = 1), p).

IVS2μsatA9 allele versus other alleles.