Persistent Microchimerism in Peripheral Blood Mononuclear cell Subsets in Healthy Women and Women With Scleroderma
| . | CD3 . | CD56/16 . | CD14 . | CD19 . |
|---|---|---|---|---|
| NL2 | − | + | − | +† |
| NL4 | − | +† | +* | +* |
| NL44 | +‡ | − | + | −* |
| NL45 | nd | nd | − | + |
| NL47 | −‡ | +† | − | − |
| NL52 | + | − | − | − |
| NL56 | − | −* | −* | +† |
| NL61 | − | − | − | − |
| NL67 | + | + | + | + |
| Sister SSc8 | −‡ | nd | −† | −† |
| Sister SSc27 | − | −† | +† | −† |
| SSc8 | + | nd | − | − |
| SSc11 | − | +† | − | − |
| SSc20 | − | − | +† | − |
| SSc26 | +† | −* | − | +† |
| SSc27 | − | +* | + | −* |
| SSc29 | −† | +† | −† | nd |
| SSc32 | + | + | − | − |
| SSc4 | − | + | − | − |
| SSc33 | − | − | − | + |
| . | CD3 . | CD56/16 . | CD14 . | CD19 . |
|---|---|---|---|---|
| NL2 | − | + | − | +† |
| NL4 | − | +† | +* | +* |
| NL44 | +‡ | − | + | −* |
| NL45 | nd | nd | − | + |
| NL47 | −‡ | +† | − | − |
| NL52 | + | − | − | − |
| NL56 | − | −* | −* | +† |
| NL61 | − | − | − | − |
| NL67 | + | + | + | + |
| Sister SSc8 | −‡ | nd | −† | −† |
| Sister SSc27 | − | −† | +† | −† |
| SSc8 | + | nd | − | − |
| SSc11 | − | +† | − | − |
| SSc20 | − | − | +† | − |
| SSc26 | +† | −* | − | +† |
| SSc27 | − | +* | + | −* |
| SSc29 | −† | +† | −† | nd |
| SSc32 | + | + | − | − |
| SSc4 | − | + | − | − |
| SSc33 | − | − | − | + |
DNA extracted from 0.5 × 105 sorted cells was tested unless otherwise noted. The distribution of Y chromosome PCR-positive and -negative PBMC subsets for 18 women who previously gave birth to at least one son. Two patients (SSc33 and SSc4) had not given birth to a son, but had a history of prior pregnancy loss and/or blood transfusion. All women were positive for Y chromosome–specific DNA upon analysis of PBMC.
Abbreviation: nd = not done.
0.2 to less than 0.5 × 105 cells were tested.
Greater than 0.5 × 105 to less than 0.9 × 105 were tested.
Between 0.9 × 105 and 1.8 × 105 cells were tested.