Total Nucleated Cellularity and Absolute Number of Progenitors From the BM and Spleen of CCR2 (−/−) and CCR2 (+/+) Mice
. | Nucleated Cells ×10−6per Organ . | Absolute Numbers of Progenitors ×10−3 per Organ . | ||
---|---|---|---|---|
CFU-GM . | BFU-E . | CFU-GEMM . | ||
Femoral marrow | ||||
+/+ | 22.8 ± 1.6 | 40.7 ± 6.1 | 13.4 ± 1.7 | 3.2 ± 0.8 |
−/− | 21.1 ± 1.4 | 49.1 ± 6.7 | 10.9 ± 1.5 | 4.0 ± 0.8 |
P values | (NS) | (NS) | (NS) | (NS) |
Spleen | ||||
+/+ | 103.1 ± 7.7 | 5.1 ± 0.8 | 6.3 ± 1.0 | 0.6 ± 0.3 |
−/− | 100.9 ± 11.2 | 5.8 ± 1.5 | 7.3 ± 1.7 | 0.8 ± 0.3 |
P values | (NS) | (NS) | (NS) | (NS) |
. | Nucleated Cells ×10−6per Organ . | Absolute Numbers of Progenitors ×10−3 per Organ . | ||
---|---|---|---|---|
CFU-GM . | BFU-E . | CFU-GEMM . | ||
Femoral marrow | ||||
+/+ | 22.8 ± 1.6 | 40.7 ± 6.1 | 13.4 ± 1.7 | 3.2 ± 0.8 |
−/− | 21.1 ± 1.4 | 49.1 ± 6.7 | 10.9 ± 1.5 | 4.0 ± 0.8 |
P values | (NS) | (NS) | (NS) | (NS) |
Spleen | ||||
+/+ | 103.1 ± 7.7 | 5.1 ± 0.8 | 6.3 ± 1.0 | 0.6 ± 0.3 |
−/− | 100.9 ± 11.2 | 5.8 ± 1.5 | 7.3 ± 1.7 | 0.8 ± 0.3 |
P values | (NS) | (NS) | (NS) | (NS) |
Results shown are the mean ± 1 SEM for a total of 11 CCR2 (−/−) and 8 CCR2 (+/+) mice from two experiments in which each mouse was assessed individually. MPC were stimulated in vitro as denoted in the legend to Table 1.
Abbreviation: NS, P > .05.