Table 2.

Detection of Proviral-Specific Sequences in Marrow-Derived Hematopoietic Colonies (CFU-GM and BFU-E) From MPS I Dogs at Time Points Postinfusion

Dogs Time Postinfusion (mo)*
1-4 5-8 9-12 13-24
M2  3/40 (7.5%) 2/47 (4.3%)  1/37 (4.3%)  3/51 (5.9%)  
M3 1/78 (1.4%)  5/63 (7.9%)  1/40 (2.5%)  2/72 (2.7%) 
M4  3/50 (6.0%)  1/27 (3.7%)  1/40 (2.5%) 2/52 (3.8%)  
M5  2/80 (2.5%)  2/100 (2.0%) 1/48 (2.1%)  NA  
M6  9/191 (4.7%) 2/24 (8.3%)  7/128 (5.5%)  3/120 (2.5%) 
Dogs Time Postinfusion (mo)*
1-4 5-8 9-12 13-24
M2  3/40 (7.5%) 2/47 (4.3%)  1/37 (4.3%)  3/51 (5.9%)  
M3 1/78 (1.4%)  5/63 (7.9%)  1/40 (2.5%)  2/72 (2.7%) 
M4  3/50 (6.0%)  1/27 (3.7%)  1/40 (2.5%) 2/52 (3.8%)  
M5  2/80 (2.5%)  2/100 (2.0%) 1/48 (2.1%)  NA  
M6  9/191 (4.7%) 2/24 (8.3%)  7/128 (5.5%)  3/120 (2.5%) 

Where colonies were available for multiple time points during each range of times, the number of colonies were added together.

Abbreviation: NA, sample not available because the dog was killed before this time point.

*

Time points are calculated from the first infusion.

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