Differentiation of M1 Cells Expressing GM-CSFR-LIFR and GM-CSFRβ-LIFR
| Cytokine . | (ng/mL) . | Phagocytic Cells (%) . |
|---|---|---|
| None | 1.3 ± 0.7* | |
| GM-CSF | 2.5 | 27.5 ± 9.0 |
| GM-CSF | 5 | 36.8 ± 4.3 |
| GM-CSF | 10 | 48.0 ± 6.0 |
| LIF | 2 | 22.8 ± 4.8 |
| IL-6 | 10 | 39.4 ± 7.6 |
| Cytokine . | (ng/mL) . | Phagocytic Cells (%) . |
|---|---|---|
| None | 1.3 ± 0.7* | |
| GM-CSF | 2.5 | 27.5 ± 9.0 |
| GM-CSF | 5 | 36.8 ± 4.3 |
| GM-CSF | 10 | 48.0 ± 6.0 |
| LIF | 2 | 22.8 ± 4.8 |
| IL-6 | 10 | 39.4 ± 7.6 |
Cells were incubated with cytokines for 2 days. Phagocytic activity of the cells was assayed as described in Materials and Methods.
Each value is the mean of duplicate determinations ± standard error.