Table 3.

Production of GM-CSF In Vitro by Organs From βc+/+ and βc−/− Mice

Organ GM-CSF ng/mL
βc+/+βc−/−
Salivary gland 0,0  0.3,0  
Thymus  16,16,8  16,32,16  
Lungs 32,1024,256  32,512,256  
Heart  16,32,2  4,8,1 
Liver  0,0,0  0,0,0  
Spleen  1,4,0.5  2,1,0 
Kidney  0,0,0  0,0,0  
Muscle  4,4,0  0.5,0,0.5 
Bone marrow  0,0,0  1,0,0  
Bone shaft  2,0.3,1 4,0.5,4  
Uterus  0  0  
Brain  0,0,0 0,0,0 
Organ GM-CSF ng/mL
βc+/+βc−/−
Salivary gland 0,0  0.3,0  
Thymus  16,16,8  16,32,16  
Lungs 32,1024,256  32,512,256  
Heart  16,32,2  4,8,1 
Liver  0,0,0  0,0,0  
Spleen  1,4,0.5  2,1,0 
Kidney  0,0,0  0,0,0  
Muscle  4,4,0  0.5,0,0.5 
Bone marrow  0,0,0  1,0,0  
Bone shaft  2,0.3,1 4,0.5,4  
Uterus  0  0  
Brain  0,0,0 0,0,0 

Individual values represent data from the bioassay of medium conditioned for 4 days by the entire organ from separate female mice aged 2 to 3 months.

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