Table 1. HLA-DR53 Restriction of the... | American Society of Hematology

Table 1.

HLA-DR53 Restriction of the Proliferative Response of HO-1 to the DEK-CAN Fusion Peptide

Clone	APC	MoAb Added	Peptide Stimulation	Proliferative Response (cpm) (mean ± SD)
Experiment No. 1^*
HO-1	Auto PBMCs	None	+	23,084 ± 1,395
			−	129 ± 24
		Anti–HLA-DR	+	209 ± 15
		Anti–HLA-DQ	+	29,599 ± 1,461
		Anti–HLA-DP	+	18,138 ± 151
Experiment No. 2^†
HO-1	None		+	604 ± 48
			−	89 ± 8
	L-Neo		+	271 ± 25
			−	213 ± 20
	L-DR4		+	640 ± 139
			−	764 ± 150
	L-DR53		+	24,475 ± 1,227
			−	242 ± 46
None	L-DR53		+	367 ± 188
			−	227 ± 25

Clone	APC	MoAb Added	Peptide Stimulation	Proliferative Response (cpm) (mean ± SD)
Experiment No. 1^*
HO-1	Auto PBMCs	None	+	23,084 ± 1,395
			−	129 ± 24
		Anti–HLA-DR	+	209 ± 15
		Anti–HLA-DQ	+	29,599 ± 1,461
		Anti–HLA-DP	+	18,138 ± 151
Experiment No. 2^†
HO-1	None		+	604 ± 48
			−	89 ± 8
	L-Neo		+	271 ± 25
			−	213 ± 20
	L-DR4		+	640 ± 139
			−	764 ± 150
	L-DR53		+	24,475 ± 1,227
			−	242 ± 46
None	L-DR53		+	367 ± 188
			−	227 ± 25

Incorporation of ³H-TdR into HO-1 cells was determined in the presence of autologous APCs with or without DEK-CAN peptide and with or without anti-HLA MoAb.

†

Incorporation of ³H-TdR into HO-1 cells was determined in the presence or absence of various types of APC with or without DEK-CAN peptide.

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