Immunohistochemical Evaluation of Apoptosis and Proliferation-Related Gene Expression
| Animal No. . | Bcl-2 . | Mcl-1 . | Bax . | Bak . | p53 . | Waf-1 . | CD954-150 . | Ki67 . |
|---|---|---|---|---|---|---|---|---|
| 1 | ++ | − | ++ | − | + | + | + | ++ |
| 2 | ++ | ++ | +++ | + | + | + | ND | ++ |
| 3 | ++ | ++ | ++ | ++ | + | + | ++ | ++ |
| 4 | ++ | ++ | + | ++ | + | ++ | ND | ++ |
| 5 | ++ | ND | ND | ND | − | − | ND | ND |
| 6 | ++ | ND | + | ++ | + | + | ++ | ++ |
| 7 | ++ | + | ++ | ++ | + | ++ | + | ++ |
| 8 | ++ | + | + | ++ | − | + | ND | − |
| 9 | − | +++ | ++ | + | ++ | + | + | +++ |
| 10 | ++ | ++ | +++ | ++ | − | + | + | ++ |
| Animal No. . | Bcl-2 . | Mcl-1 . | Bax . | Bak . | p53 . | Waf-1 . | CD954-150 . | Ki67 . |
|---|---|---|---|---|---|---|---|---|
| 1 | ++ | − | ++ | − | + | + | + | ++ |
| 2 | ++ | ++ | +++ | + | + | + | ND | ++ |
| 3 | ++ | ++ | ++ | ++ | + | + | ++ | ++ |
| 4 | ++ | ++ | + | ++ | + | ++ | ND | ++ |
| 5 | ++ | ND | ND | ND | − | − | ND | ND |
| 6 | ++ | ND | + | ++ | + | + | ++ | ++ |
| 7 | ++ | + | ++ | ++ | + | ++ | + | ++ |
| 8 | ++ | + | + | ++ | − | + | ND | − |
| 9 | − | +++ | ++ | + | ++ | + | + | +++ |
| 10 | ++ | ++ | +++ | ++ | − | + | + | ++ |
CD95 positive only in infiltrating lymphocytes, negative in tumor cells.