Table 4.

Effect of Different IVIG Preparations on In Vitro Phagocytic Activity of Human Granulocytes

Test Sample Phagocytosis-Efficiency of Granulocytes
Plasma + IVIgM4-150 72.3 ± 0.84-151 
Plasma + Pentaglobin 73.2 ± 0.8  
Plasma + IVIgG  73.6 ± 0.7  
Plasma alone  78.0 ± 0.6  
Heat-inactivated plasma  17.5 ± 0.5 
PBS  1.2 ± 0.4 
Test Sample Phagocytosis-Efficiency of Granulocytes
Plasma + IVIgM4-150 72.3 ± 0.84-151 
Plasma + Pentaglobin 73.2 ± 0.8  
Plasma + IVIgG  73.6 ± 0.7  
Plasma alone  78.0 ± 0.6  
Heat-inactivated plasma  17.5 ± 0.5 
PBS  1.2 ± 0.4 
F4-150

Concentration of IVIGs: 25 mg/mL.

F4-151

Expressed as percentage of granulocytes that had ingested FITC-labeled E coli, with indication of the standard deviation. IVIG preparations were mixed with an equal volume of fresh plasma, added to unfractionated blood cells and FITC-labeled E coli and incubated for 10 minutes at 37°C. Phagocytosis activity of granulocytes was analyzed by FACS.

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