Effect of Different IVIG Preparations on In Vitro Phagocytic Activity of Human Granulocytes
Test Sample . | Phagocytosis-Efficiency of Granulocytes . |
---|---|
Plasma + IVIgM4-150 | 72.3 ± 0.84-151 |
Plasma + Pentaglobin | 73.2 ± 0.8 |
Plasma + IVIgG | 73.6 ± 0.7 |
Plasma alone | 78.0 ± 0.6 |
Heat-inactivated plasma | 17.5 ± 0.5 |
PBS | 1.2 ± 0.4 |
Test Sample . | Phagocytosis-Efficiency of Granulocytes . |
---|---|
Plasma + IVIgM4-150 | 72.3 ± 0.84-151 |
Plasma + Pentaglobin | 73.2 ± 0.8 |
Plasma + IVIgG | 73.6 ± 0.7 |
Plasma alone | 78.0 ± 0.6 |
Heat-inactivated plasma | 17.5 ± 0.5 |
PBS | 1.2 ± 0.4 |
Concentration of IVIGs: 25 mg/mL.
Expressed as percentage of granulocytes that had ingested FITC-labeled E coli, with indication of the standard deviation. IVIG preparations were mixed with an equal volume of fresh plasma, added to unfractionated blood cells and FITC-labeled E coli and incubated for 10 minutes at 37°C. Phagocytosis activity of granulocytes was analyzed by FACS.