Table 1.

Group B Patients: Pretransplant Characteristics

Characteristic Value
Age (yr)  
 Range  17-35 
 Mean (standard deviation)  21.5 (3.8)  
Gender female 39  
Previous red blood cell transfusions (no.)  
 Range  58-900  
 Mean (standard deviation)  362.0 (132.4) 
Age at first transfusion (mo)  
 Range   2-324  
 Mean (standard deviation)  28.5 (49.3) 
Age at first chelation (mo)  
 Range    3-324 
 Mean (standard deviation)  107.0 (73.7)  
Chelation index  
 Range   0-97  
 Mean (standard deviation)  55.0 (33.0)  
 No. of patients with index of 0 20  
Serum ferritin (μg/L)  
 Range   322-8,106  
 Mean (standard deviation) 2241 (1620)  
Chronic active hepatitis (CAH) 
 No. of patients with CAH  35  
Unbound iron-binding capacity (μg/dL) (values greater than 0 were available for 37 patients*
 Range    1-147  
 Mean (standard deviation) 30.0 (34.4)  
Liver iron concentration (mg/g) (normal values are <1.6 mg/g) (values were not available for 10 patients) 
 Range   1.4-41.9  
 Mean (standard deviation) 14.4 (10.2) 
Characteristic Value
Age (yr)  
 Range  17-35 
 Mean (standard deviation)  21.5 (3.8)  
Gender female 39  
Previous red blood cell transfusions (no.)  
 Range  58-900  
 Mean (standard deviation)  362.0 (132.4) 
Age at first transfusion (mo)  
 Range   2-324  
 Mean (standard deviation)  28.5 (49.3) 
Age at first chelation (mo)  
 Range    3-324 
 Mean (standard deviation)  107.0 (73.7)  
Chelation index  
 Range   0-97  
 Mean (standard deviation)  55.0 (33.0)  
 No. of patients with index of 0 20  
Serum ferritin (μg/L)  
 Range   322-8,106  
 Mean (standard deviation) 2241 (1620)  
Chronic active hepatitis (CAH) 
 No. of patients with CAH  35  
Unbound iron-binding capacity (μg/dL) (values greater than 0 were available for 37 patients*
 Range    1-147  
 Mean (standard deviation) 30.0 (34.4)  
Liver iron concentration (mg/g) (normal values are <1.6 mg/g) (values were not available for 10 patients) 
 Range   1.4-41.9  
 Mean (standard deviation) 14.4 (10.2) 

The iron-binding capacity of 38 patients was completely saturated.

*

Values were not available for 12 patients.

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