Table 4.

Causes of Treatment Failure for PSC-MEC Induction Therapy in Poor-Risk AML Patients in This Study

Cohort I Cohort II Total
Death during hypoplasia  
 Infection  3  6  9  
 Arrhythmia 0  14-150 1  
 Myocardial infarction  14-151 1  
 Hemorrhage  0  1 
Leukemia-associated  
 Regrowth resistance  1  8  
 Refractory  0  1  1  
 
Total  4  17 21 
Cohort I Cohort II Total
Death during hypoplasia  
 Infection  3  6  9  
 Arrhythmia 0  14-150 1  
 Myocardial infarction  14-151 1  
 Hemorrhage  0  1 
Leukemia-associated  
 Regrowth resistance  1  8  
 Refractory  0  1  1  
 
Total  4  17 21 
F4-150

Fatal arrhythmia in the setting of severe hypokalemia in a patient receiving amphotericin infusion.

F4-151

Fatal acute myocardial infarction in the setting of a severe hemolytic anemia.

Fatal subdural hematoma while thrombocytopenic.

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