Table 1.

Characteristics of the Two Cohorts of LT-NP (ALT) and Standard Progressors (IMMUNOCO) at Inclusion

ALT (LT-NPs) n = 70 IMMUNOCO (progressors) n = 83 P Value*
Cohort started 1996  1991-1992  
Inclusion criteria  18 yr of age or more  18 yr of age or more  
 and  
 Time since first HIV+ test equal to or above 8 yr  Any time  
 and  
 No AIDS symptoms (stage A)  Any stage  
 and  
 No antiviral treatment  With or without antiviral treatment  
 and  and  
 CD4 counts >600/μL during last 5 yr  CD4 counts >150/μL at entry  
Sex (% men)  53 (76%) 67 (81%)  .453  
Time since first HIV+test (yr) 9.7 (7.8-12.4)  4.3 (0.2-9.1) <.001  
Age at first HIV+ test (yr) 27.8 (12.2-56.1)  29.7 (18.6-49.2)  .096  
Transmission group  
 Homosexual/bisexual men  37 (53%) 56 (67%)  .181  
 Heterosexuals  6 (9%) 8 (10%)  
IV drug users  16 (23%) 13 (16%)  
Others  11 (15%) 6 (7%)  
No. of CD4 cells/μL 672 (278-1,286)  361 (115-1,331) <.001  
No. of CD8 cells/μL 955 (391-2,265)  949 (242-2,534) .502 
ALT (LT-NPs) n = 70 IMMUNOCO (progressors) n = 83 P Value*
Cohort started 1996  1991-1992  
Inclusion criteria  18 yr of age or more  18 yr of age or more  
 and  
 Time since first HIV+ test equal to or above 8 yr  Any time  
 and  
 No AIDS symptoms (stage A)  Any stage  
 and  
 No antiviral treatment  With or without antiviral treatment  
 and  and  
 CD4 counts >600/μL during last 5 yr  CD4 counts >150/μL at entry  
Sex (% men)  53 (76%) 67 (81%)  .453  
Time since first HIV+test (yr) 9.7 (7.8-12.4)  4.3 (0.2-9.1) <.001  
Age at first HIV+ test (yr) 27.8 (12.2-56.1)  29.7 (18.6-49.2)  .096  
Transmission group  
 Homosexual/bisexual men  37 (53%) 56 (67%)  .181  
 Heterosexuals  6 (9%) 8 (10%)  
IV drug users  16 (23%) 13 (16%)  
Others  11 (15%) 6 (7%)  
No. of CD4 cells/μL 672 (278-1,286)  361 (115-1,331) <.001  
No. of CD8 cells/μL 955 (391-2,265)  949 (242-2,534) .502 
*

P values were computed using Mann-Whitney and the χ2 tests.

All CD4 and CD8 cell measures were performed in our laboratory; data is presented as median values with, in parentheses, the minimum-maximum values. All participants of both cohorts gave consent for the studies.

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