Characteristics and Genotype Data in Cases of Venous Thromboembolism and Control Patients
| . | VTE Patients . | Controls . | P . |
|---|---|---|---|
| Number | 221 | 254 | |
| DVT only:PE | 122:99 | ||
| Male:female | 127:94 | 147:107 | NS |
| Age (yr) | 62 (28-74) | 60 (27-67) | <.005 |
| History of malignancy | 28 (13%) | 9 (4%) | <.005 |
| Factor XIII Val34Leu genotype | .007 | ||
| Val/Val (G/G) | 137 [63 (57-70)%] | 123 [49 (43-55)%] | |
| Val/Leu (G/T) | 68 [31 (25-38)%] | 107 [43 (36-49)%] | |
| Leu/Leu (T/T) | 12 [6 (3-7)%] | 22 [9 (5-12)%] | |
| Factor V genotype | .03 | ||
| Wild-type | 191 [89 (85-93)%] | 237 [94 (91-97)%] | |
| FV:Q506 carriers | 24 [11 (7-15)%] | 15 [6 (3-9)%] | |
| Prothrombin 20210A genotype | .10 | ||
| Wild-type | 218 | 254 | |
| G-A 20210A mutation carriers | 3 | 0 |
| . | VTE Patients . | Controls . | P . |
|---|---|---|---|
| Number | 221 | 254 | |
| DVT only:PE | 122:99 | ||
| Male:female | 127:94 | 147:107 | NS |
| Age (yr) | 62 (28-74) | 60 (27-67) | <.005 |
| History of malignancy | 28 (13%) | 9 (4%) | <.005 |
| Factor XIII Val34Leu genotype | .007 | ||
| Val/Val (G/G) | 137 [63 (57-70)%] | 123 [49 (43-55)%] | |
| Val/Leu (G/T) | 68 [31 (25-38)%] | 107 [43 (36-49)%] | |
| Leu/Leu (T/T) | 12 [6 (3-7)%] | 22 [9 (5-12)%] | |
| Factor V genotype | .03 | ||
| Wild-type | 191 [89 (85-93)%] | 237 [94 (91-97)%] | |
| FV:Q506 carriers | 24 [11 (7-15)%] | 15 [6 (3-9)%] | |
| Prothrombin 20210A genotype | .10 | ||
| Wild-type | 218 | 254 | |
| G-A 20210A mutation carriers | 3 | 0 |
Values for age are median (range). Square brackets enclose percentages and 95% confidence intervals.
Abbreviation: NS, not significant.