Table 1. Patient Characteristics and... | American Society of Hematology

Table 1.

Patient Characteristics and Clinical Data

Patient No.	Age and Sex	Percentage of Positive Cells^*						TCR β	NK CellMediated Cytolysis^†	Clinical Course
Patient No.	Age and Sex	CD2	CD3	CD4	CD8	CD16	CD56	TCR β	NK CellMediated Cytolysis^†	Clinical Course
1	62F	98	3	2	90	94	95	G	81	I
2	51F	92	21	15	18	52	76	G	63	I
3	34M	ND	35	17	41	33	51	G	ND	I
4	10M	89	20	12	8	64	58	G	ND	I
5	51F	89	7	6	8	89	8	G	77	I
6	66M	92	18	17	14	78	6	G	72	I
7	28M	93	10	5	3	1	96	G	1	A
8	57M	98	4	5	3	59	89	G	71	A
9	67F	87	6	3	4	10	80	G	0	A

Patient No.	Age and Sex	Percentage of Positive Cells^*						TCR β	NK CellMediated Cytolysis^†	Clinical Course
Patient No.	Age and Sex	CD2	CD3	CD4	CD8	CD16	CD56	TCR β	NK CellMediated Cytolysis^†	Clinical Course
1	62F	98	3	2	90	94	95	G	81	I
2	51F	92	21	15	18	52	76	G	63	I
3	34M	ND	35	17	41	33	51	G	ND	I
4	10M	89	20	12	8	64	58	G	ND	I
5	51F	89	7	6	8	89	8	G	77	I
6	66M	92	18	17	14	78	6	G	72	I
7	28M	93	10	5	3	1	96	G	1	A
8	57M	98	4	5	3	59	89	G	71	A
9	67F	87	6	3	4	10	80	G	0	A

Patients 1 to 6 had indolent NK cell-lineage granular lymphocyte-proliferative disorder (NK-GLPD), patient 7 had aggressive NK cell leukemia, and patients 8 and 9 had nasal NK cell lymphoma.

Abbreviations: ND, not done; G, germ-line configuration; I, indolent; A, aggressive.

Surface phenotypes of PBMC (patients 1 through 7 and 9) or lymph node (patient 8) are shown in percentages.

†

Cytotoxicity was assayed against K562 target cells at an effector-to-target cell ratio of 20:1 with 4 hours of incubation.

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