Comparison of the Level of Genotypic Mismatching at HLA-A and HLA-B Loci Following High-Resolution DNA Typing for HLA-A and HLA-B by PCR-SSOP
| . | Matching Status by Using HLA-A and HLA-B Serology and HLA-DRB1 by DNA Typing . | ||
|---|---|---|---|
| 6/6 Matched URD . | 5/6 Matched URD . | All URD4-150 . | |
| Matched for both HLA-A alleles | 153 (81.82%) | 88 (53.66%) | 290 (59.92%) |
| Matched for both HLB-B alleles | 120 (64.17%) | 88 (53.66%) | 242 (50.00%) |
| Ratio of HLA-A mismatched v matched (MMA) | 34 v 153 (18.2/81.8%) | 76 v 88 (46.3/53.7%) | 194 v 290 (40.1/59.9%) |
| Ratio of HLA-B mismatchedv matched (MMB) | 67 v 120 (35.8/64.2%) | 76 v 88 (46.3/53.7%) | 242 v 242 (50.0/50.0%) |
| MMAv MMB | P < .01 | P > .9 | P < .01 |
| . | Matching Status by Using HLA-A and HLA-B Serology and HLA-DRB1 by DNA Typing . | ||
|---|---|---|---|
| 6/6 Matched URD . | 5/6 Matched URD . | All URD4-150 . | |
| Matched for both HLA-A alleles | 153 (81.82%) | 88 (53.66%) | 290 (59.92%) |
| Matched for both HLB-B alleles | 120 (64.17%) | 88 (53.66%) | 242 (50.00%) |
| Ratio of HLA-A mismatched v matched (MMA) | 34 v 153 (18.2/81.8%) | 76 v 88 (46.3/53.7%) | 194 v 290 (40.1/59.9%) |
| Ratio of HLA-B mismatchedv matched (MMB) | 67 v 120 (35.8/64.2%) | 76 v 88 (46.3/53.7%) | 242 v 242 (50.0/50.0%) |
| MMAv MMB | P < .01 | P > .9 | P < .01 |
Includes 4/6 URD; to increase clarity and save space 4/6 data is not included in the table.