The top two lines line of each group indicate the homologous genomic segment and sequence number, respectively, Koop et al,14 Rowen et al,15 and Slightom et al,16 and the third line indicates the actual sequence derived from the patients. Where present, the fourth, fifth, and sixth lines indicate putative splice sites within the 3′ gene segments. Shaded regions indicate homologous regions that may direct aberrant splicing.