Productive Sequences: TCRβ
| Clone No. . | No. of Unique mRNA Transcripts Identified . | Vβ . | NDN . | Jβ . | CDR3 Length3-151 . | ||||
|---|---|---|---|---|---|---|---|---|---|
| Case 1 | |||||||||
| 1 | 3 | 3.13-150 | . . . | CASSL | TGG | TEAFFG | . . . | 1.1 | 8 |
| 2 | 2 | 14.1 | . . . | C | MGL | QFFG | . . . | 2.1 | 2 |
| 3 | 1 | 14.13-150 | . . . | CASSL | QG | TEAFFG | . . . | 1.1 | 7 |
| 4 | 1 | 5.13-150 | . . . | CASSL | AGSQRRA | SYEQYFG | . . . | 2.73-150 | 13 |
| 5 | 1 | 5.13-150 | . . . | CASSL | AR | NTEAFFG | . . . | 1.13-150 | 8 |
| 6 | 1 | 5.13-150 | . . . | CASSL | HRGGK | NQPQHFG | . . . | 1.5 | 11 |
| 7 | 1 | ? | . . . | CASS | QGLGKG | EAFFG | . . . | 1.1 | 9 |
| c | — | 17.1 | . . . | CASS | PGQGFG | YNEGFFG | . . . | 2.1 | 9 |
| Case 2 | |||||||||
| 1 | 4 | 12.23-150 | . . . | CAISES | KDRGS | ETQYFG | . . . | 2.5 | 11 |
| 2 | 1 | 8.1 | . . . | CAS | TMDRV | NQPQHFG | . . . | 1.5 | 9 |
| 3 | 1 | 13.3 | . . . | CAS | IMDVF | TEAFFG | . . . | 1.1 | 8 |
| 4 | 1 | 8.13-150 | . . . | CASSL | TAQL | QYFG | . . . | 2.4 | 7 |
| 5 | 1 | 6.5 | . . . | CASS | YGQR | EQYFG | . . . | 2.7 | 7 |
| 6 | 1 | 13.6 | . . . | CASS | LDKAG | TEAFFG | . . . | 1.1 | 9 |
| 7 | 1 | 13.63-150 | . . . | CASSY | VGL | NTEAFFG | . . . | 1.13-150 | 9 |
| 8 | 1 | 2.1 | . . | CSA | PRVG | GELFFG | . . . | 2.2 | 7 |
| 9 | 1 | 21.43-150 | . . . | CASSL | RIT | NTGEIFFG | . . . | 2.23-150 | 10 |
| 10 | 1 | 22.1 | . . . | CAS | TRLTTT | NEQFFG | . . . | 2.1 | 9 |
| Case 3 | |||||||||
| 1 | 14 | 15.13-150 | . . . | CATSDL | GG | NQPQHFG | . . . | 1.5 | 9 |
| 2 | 7 | 11.1 | . . . | CASS | ITGD | TEAFFG | . . . | 1.1 | 8 |
| 3 | 3 | 3.13-150 | . . . | CASSL | GG | YGYTFG | . . . | 1.2 | 7 |
| Case 4 | |||||||||
| 1 | 5 | 3.1 | . . . | CASS | WDN | YEQYFG | . . . | 2.7 | 7 |
| 2 | 1 | 3.13-150 | . . . | CASSL | --- | STDTQYFG | . . . | 2.33-150 | 7 |
| 3 | 1 | 6.7 | . . . | CASS | LRTSRRV | EQYFG | . . . | 2.7 | 11 |
| 4 | 2 | 5.1 | . . . | CASS | PSGGL | NQPQHFG | . . . | 1.5 | 10 |
| c | — | 3.1 | . . . | CASS | RG | TEAFFG | . . . | 1.1 | 7 |
| Case 5 | |||||||||
| 1 | 1 | 6.5 | . . . | CASS | PGTA | NTEAFFG | . . . | 1.13-150 | 9 |
| Case 6 | |||||||||
| 1 | 1 | 6.43-150 | . . . | CASSL | GLGPH | EQYFG | . . . | 2.7 | 9 |
| Case 7 | |||||||||
| — | none | ||||||||
| Clone No. . | No. of Unique mRNA Transcripts Identified . | Vβ . | NDN . | Jβ . | CDR3 Length3-151 . | ||||
|---|---|---|---|---|---|---|---|---|---|
| Case 1 | |||||||||
| 1 | 3 | 3.13-150 | . . . | CASSL | TGG | TEAFFG | . . . | 1.1 | 8 |
| 2 | 2 | 14.1 | . . . | C | MGL | QFFG | . . . | 2.1 | 2 |
| 3 | 1 | 14.13-150 | . . . | CASSL | QG | TEAFFG | . . . | 1.1 | 7 |
| 4 | 1 | 5.13-150 | . . . | CASSL | AGSQRRA | SYEQYFG | . . . | 2.73-150 | 13 |
| 5 | 1 | 5.13-150 | . . . | CASSL | AR | NTEAFFG | . . . | 1.13-150 | 8 |
| 6 | 1 | 5.13-150 | . . . | CASSL | HRGGK | NQPQHFG | . . . | 1.5 | 11 |
| 7 | 1 | ? | . . . | CASS | QGLGKG | EAFFG | . . . | 1.1 | 9 |
| c | — | 17.1 | . . . | CASS | PGQGFG | YNEGFFG | . . . | 2.1 | 9 |
| Case 2 | |||||||||
| 1 | 4 | 12.23-150 | . . . | CAISES | KDRGS | ETQYFG | . . . | 2.5 | 11 |
| 2 | 1 | 8.1 | . . . | CAS | TMDRV | NQPQHFG | . . . | 1.5 | 9 |
| 3 | 1 | 13.3 | . . . | CAS | IMDVF | TEAFFG | . . . | 1.1 | 8 |
| 4 | 1 | 8.13-150 | . . . | CASSL | TAQL | QYFG | . . . | 2.4 | 7 |
| 5 | 1 | 6.5 | . . . | CASS | YGQR | EQYFG | . . . | 2.7 | 7 |
| 6 | 1 | 13.6 | . . . | CASS | LDKAG | TEAFFG | . . . | 1.1 | 9 |
| 7 | 1 | 13.63-150 | . . . | CASSY | VGL | NTEAFFG | . . . | 1.13-150 | 9 |
| 8 | 1 | 2.1 | . . | CSA | PRVG | GELFFG | . . . | 2.2 | 7 |
| 9 | 1 | 21.43-150 | . . . | CASSL | RIT | NTGEIFFG | . . . | 2.23-150 | 10 |
| 10 | 1 | 22.1 | . . . | CAS | TRLTTT | NEQFFG | . . . | 2.1 | 9 |
| Case 3 | |||||||||
| 1 | 14 | 15.13-150 | . . . | CATSDL | GG | NQPQHFG | . . . | 1.5 | 9 |
| 2 | 7 | 11.1 | . . . | CASS | ITGD | TEAFFG | . . . | 1.1 | 8 |
| 3 | 3 | 3.13-150 | . . . | CASSL | GG | YGYTFG | . . . | 1.2 | 7 |
| Case 4 | |||||||||
| 1 | 5 | 3.1 | . . . | CASS | WDN | YEQYFG | . . . | 2.7 | 7 |
| 2 | 1 | 3.13-150 | . . . | CASSL | --- | STDTQYFG | . . . | 2.33-150 | 7 |
| 3 | 1 | 6.7 | . . . | CASS | LRTSRRV | EQYFG | . . . | 2.7 | 11 |
| 4 | 2 | 5.1 | . . . | CASS | PSGGL | NQPQHFG | . . . | 1.5 | 10 |
| c | — | 3.1 | . . . | CASS | RG | TEAFFG | . . . | 1.1 | 7 |
| Case 5 | |||||||||
| 1 | 1 | 6.5 | . . . | CASS | PGTA | NTEAFFG | . . . | 1.13-150 | 9 |
| Case 6 | |||||||||
| 1 | 1 | 6.43-150 | . . . | CASSL | GLGPH | EQYFG | . . . | 2.7 | 9 |
| Case 7 | |||||||||
| — | none | ||||||||
Abbreviations: ---, absence of any D- or N-region–encoded sequences; _, germline D-region–encoded amino acids; c, the TCR was derived from a T-cell clone.
Indicates usage of full-length germline-encoded sequences.
Range, 7 to 13; mean, 8.62; median, 9; variance, 2.5; skew, 0.83; kurtosis, 0.55.