Prognostic Factors at Diagnosis
| Parameter . | N . | EFS (mos) . | P . | OS (mos) . | P . |
|---|---|---|---|---|---|
| Karyotype | |||||
| No Δ 11/13 | 182 | 52 | .0002 | 84+ | .0001 |
| Δ 11/13 | 49 | 25 | 34 | ||
| Bartl grade | |||||
| ≤1 | 142 | 53 | .002 | 81+ | .0004 |
| >1 | 60 | 28 | 43 | ||
| β2M (mg/L) | |||||
| ≤4.0 | 161 | 51 | .0002 | 84+ | .003 |
| >4.0 | 68 | 26 | 50 | ||
| CRP (mg/L) | |||||
| ≤4.0 | 120 | 57 | .0003 | 84+ | .008 |
| >4.0 | 93 | 30 | 62 | ||
| Hgb (g/dL) | |||||
| >10.0 | 151 | 53 | .0008 | 84+ | .009 |
| ≤10.0 | 80 | 29 | 60 | ||
| Creat (g/dL) | |||||
| ≤2.0 | 211 | 46 | .05 | 84+ | .01 |
| >2.0 | 20 | 28 | 44 | ||
| Albumin (g/dL) | |||||
| >3.5 | 158 | 43 | .9 | 84+ | .02 |
| ≤3.5 | 73 | 52 | 55 | ||
| Isotype | |||||
| Non-Ig | 190 | 50 | .04 | 84+ | .03 |
| IgA | 41 | 33 | 47 | ||
| Age (yrs) | |||||
| ≤60 | 181 | 50 | .09 | 84+ | .03 |
| >60 | 50 | 32 | 50 | ||
| Calcium (g/dL) | |||||
| ≤11.0 | 204 | 49 | .06 | 68 | .05 |
| >11.0 | 27 | 23 | 44 | ||
| LDH (U/L) | |||||
| ≤190 | 181 | 49 | .2 | 82+ | .09 |
| >190 | 49 | 33 | 57 | ||
| BM PC (%) | |||||
| ≤50% | 121 | 50 | .1 | 80+ | .1 |
| >50% | 91 | 34 | 62 | ||
| Stage | |||||
| <III | 108 | 43 | .3 | 84+ | .2 |
| III | 123 | 46 | 65 | ||
| Sex | |||||
| Male | 143 | 41 | .5 | 68 | .4 |
| Female | 88 | 53 | 82+ | ||
| Race | |||||
| White | 206 | 43 | .7 | 65 | .6 |
| Non-white | 25 | 49 | 78+ | ||
| Total | 231 | 43 | 68 |
| Parameter . | N . | EFS (mos) . | P . | OS (mos) . | P . |
|---|---|---|---|---|---|
| Karyotype | |||||
| No Δ 11/13 | 182 | 52 | .0002 | 84+ | .0001 |
| Δ 11/13 | 49 | 25 | 34 | ||
| Bartl grade | |||||
| ≤1 | 142 | 53 | .002 | 81+ | .0004 |
| >1 | 60 | 28 | 43 | ||
| β2M (mg/L) | |||||
| ≤4.0 | 161 | 51 | .0002 | 84+ | .003 |
| >4.0 | 68 | 26 | 50 | ||
| CRP (mg/L) | |||||
| ≤4.0 | 120 | 57 | .0003 | 84+ | .008 |
| >4.0 | 93 | 30 | 62 | ||
| Hgb (g/dL) | |||||
| >10.0 | 151 | 53 | .0008 | 84+ | .009 |
| ≤10.0 | 80 | 29 | 60 | ||
| Creat (g/dL) | |||||
| ≤2.0 | 211 | 46 | .05 | 84+ | .01 |
| >2.0 | 20 | 28 | 44 | ||
| Albumin (g/dL) | |||||
| >3.5 | 158 | 43 | .9 | 84+ | .02 |
| ≤3.5 | 73 | 52 | 55 | ||
| Isotype | |||||
| Non-Ig | 190 | 50 | .04 | 84+ | .03 |
| IgA | 41 | 33 | 47 | ||
| Age (yrs) | |||||
| ≤60 | 181 | 50 | .09 | 84+ | .03 |
| >60 | 50 | 32 | 50 | ||
| Calcium (g/dL) | |||||
| ≤11.0 | 204 | 49 | .06 | 68 | .05 |
| >11.0 | 27 | 23 | 44 | ||
| LDH (U/L) | |||||
| ≤190 | 181 | 49 | .2 | 82+ | .09 |
| >190 | 49 | 33 | 57 | ||
| BM PC (%) | |||||
| ≤50% | 121 | 50 | .1 | 80+ | .1 |
| >50% | 91 | 34 | 62 | ||
| Stage | |||||
| <III | 108 | 43 | .3 | 84+ | .2 |
| III | 123 | 46 | 65 | ||
| Sex | |||||
| Male | 143 | 41 | .5 | 68 | .4 |
| Female | 88 | 53 | 82+ | ||
| Race | |||||
| White | 206 | 43 | .7 | 65 | .6 |
| Non-white | 25 | 49 | 78+ | ||
| Total | 231 | 43 | 68 |