Transendothelial Migration of Normal Hematopoietic Progenitor Cells
| Cell Line . | Antibody . | No. of Transmigrated Cells (/5 × 104 semi-purified cells) . | No. of Transmigrated CFU-GM (/5 × 104 semi-purified cells) . |
|---|---|---|---|
| LE1SVO | 7.1 ± 1.0 | 0 | |
| STR-2 | 8.3 ± 3.2 | 0 | |
| STR-4 | +Control Ig | 82.6 ± 15.6 | 17.5 ± 13.0 |
| +Anti–VLA-4 antibody | 19.7 ± 0.8 | 0 | |
| +Anti–VCAM-1 antibody | 18.8 ± 7.3 | 0 | |
| STR-10 | +Control Ig | 36.6 ± 7.6 | 10.0 ± 5.3 |
| +Anti–VCAM-1 antibody | 4.6 ± 1.2 | 1.3 ± 2.1 | |
| STR-12 | +Control Ig | 54.3 ± 1.9 | 13.0 ± 2.6 |
| +Anti–VCAM-1 antibody | 5.0 ± 1.0 | 0 |
| Cell Line . | Antibody . | No. of Transmigrated Cells (/5 × 104 semi-purified cells) . | No. of Transmigrated CFU-GM (/5 × 104 semi-purified cells) . |
|---|---|---|---|
| LE1SVO | 7.1 ± 1.0 | 0 | |
| STR-2 | 8.3 ± 3.2 | 0 | |
| STR-4 | +Control Ig | 82.6 ± 15.6 | 17.5 ± 13.0 |
| +Anti–VLA-4 antibody | 19.7 ± 0.8 | 0 | |
| +Anti–VCAM-1 antibody | 18.8 ± 7.3 | 0 | |
| STR-10 | +Control Ig | 36.6 ± 7.6 | 10.0 ± 5.3 |
| +Anti–VCAM-1 antibody | 4.6 ± 1.2 | 1.3 ± 2.1 | |
| STR-12 | +Control Ig | 54.3 ± 1.9 | 13.0 ± 2.6 |
| +Anti–VCAM-1 antibody | 5.0 ± 1.0 | 0 |