EGFP Expression of UCB Subsets
| Vector/Packaging Cell Line . | Purified CD34+Cells . | P Value* . | CD34+CD38−Population Within Purified CD34+ . | P Value† . | Purified CD34+CD38− . | PValue‡ . |
|---|---|---|---|---|---|---|
| MFG-EGFP/Am12 | 30 (8-51) (n = 13) | >.05 | 25 (15-55) (n = 9) | >.05 | 19 (8-21) (n = 4) | .02 |
| SF-EGFP/PG13 | 75 (53-84) (n = 7) | >.05 | 66 (58-81) (n = 5) | >.05 | 62 (21-71) (n = 4) | .12 |
| P value1-153 | .0001 | .003 | .02 |
| Vector/Packaging Cell Line . | Purified CD34+Cells . | P Value* . | CD34+CD38−Population Within Purified CD34+ . | P Value† . | Purified CD34+CD38− . | PValue‡ . |
|---|---|---|---|---|---|---|
| MFG-EGFP/Am12 | 30 (8-51) (n = 13) | >.05 | 25 (15-55) (n = 9) | >.05 | 19 (8-21) (n = 4) | .02 |
| SF-EGFP/PG13 | 75 (53-84) (n = 7) | >.05 | 66 (58-81) (n = 5) | >.05 | 62 (21-71) (n = 4) | .12 |
| P value1-153 | .0001 | .003 | .02 |
Results are expressed as percentages of EGFP+ cells and depicted as median (range). For statistical analysis the Mann-Whitney U-test has been used.
Comparison of the median of purified CD34+ cells and CD34+CD38− subset within the purified CD34+ population.
Comparison of the median of CD34+CD38−subset within the purified CD34+ population and purified CD34+CD38− cells.
Comparison of the median of purified CD34+ cells and purified CD34+CD38− cells.
Comparison of MFG-EGFP– and SF-EGFP–transduced cells.