Summary of Results
Time After IL-3 Withdrawal (h) . | v-ABL TK Status . | % Dead (trypan blue positive) . | Ψm(fluo- rescence units normalized to 0 h) . | Cytosolic Cyto C . | Clonogenicity (% normalized to 0 h) . |
---|---|---|---|---|---|
0 | 2 | 100 | −− | 100 | |
18 | Active | 5 | 148 | −− | 163 |
18 | Inactive | 8 | 64 | ++ | 100 |
18-42 | Inactivated at 18 h | 33 | 88 | ND | 10 |
18-42 | Activated at 18 h | 17 | 148 | + | 40 |
42 | Active | 10 | ND | 100 | |
42 | Inactive | 49 | ++ | 0 |
Time After IL-3 Withdrawal (h) . | v-ABL TK Status . | % Dead (trypan blue positive) . | Ψm(fluo- rescence units normalized to 0 h) . | Cytosolic Cyto C . | Clonogenicity (% normalized to 0 h) . |
---|---|---|---|---|---|
0 | 2 | 100 | −− | 100 | |
18 | Active | 5 | 148 | −− | 163 |
18 | Inactive | 8 | 64 | ++ | 100 |
18-42 | Inactivated at 18 h | 33 | 88 | ND | 10 |
18-42 | Activated at 18 h | 17 | 148 | + | 40 |
42 | Active | 10 | ND | 100 | |
42 | Inactive | 49 | ++ | 0 |
Results are the average of at least three independent experiments.
Abbreviation: ND, not determined.