Table 3. GM-CSF Receptors on Light... | American Society of Hematology

Table 3.

GM-CSF Receptors on Light Density JMML and CMML Peripheral Blood and Normal Marrow Cells

Patient	Disease	High-Affinity Receptors/Cell	kd × 10⁻¹¹
AJ	JMML	141	1.2
NL	JMML	ND	ND
HA	JMML	ND	ND
CF	JMML	164	0.6
PR	JMML	119	0.6
MS	JMML	310	0.6
CB	JMML	539	2
G	CMML	636	2
CL	CMML	344	1.2
RS	CMML	624	1.1
WS	CMML	188	0.8
AR	CMML	384	1.4
JT	CMML	657	2
CT	CMML	1512	1.3
LS	CMML	268	0.6
RB	CMML	1720	1.3
WB	CMML	1100	2.9
FB	CMML	490	2.9
GN	CMML	310	0.5
GW	CMML	240	0.3
RM	CMML	990	2
EB	CMML	350	2.9
KP	CMML	170	2
SB	CMML	420	1
PP	CMML	410	2
DJ	CMML	330	1
ED	CMML	890	2.6
LP	CMML	340	1.5
CAD25^3-150	Normal	525	0.4
CAD^3-150	Normal	159	1
U11802	Normal	420	0.6
U11811	Normal	580	1
U11454	Normal	16	0.3

Patient	Disease	High-Affinity Receptors/Cell	kd × 10⁻¹¹
AJ	JMML	141	1.2
NL	JMML	ND	ND
HA	JMML	ND	ND
CF	JMML	164	0.6
PR	JMML	119	0.6
MS	JMML	310	0.6
CB	JMML	539	2
G	CMML	636	2
CL	CMML	344	1.2
RS	CMML	624	1.1
WS	CMML	188	0.8
AR	CMML	384	1.4
JT	CMML	657	2
CT	CMML	1512	1.3
LS	CMML	268	0.6
RB	CMML	1720	1.3
WB	CMML	1100	2.9
FB	CMML	490	2.9
GN	CMML	310	0.5
GW	CMML	240	0.3
RM	CMML	990	2
EB	CMML	350	2.9
KP	CMML	170	2
SB	CMML	420	1
PP	CMML	410	2
DJ	CMML	330	1
ED	CMML	890	2.6
LP	CMML	340	1.5
CAD25^3-150	Normal	525	0.4
CAD^3-150	Normal	159	1
U11802	Normal	420	0.6
U11811	Normal	580	1
U11454	Normal	16	0.3

Determined by Scatchard analysis between 0.6 pmol/L and 26 pmol/L¹²⁵I-GM-CSF as described in the text. There were insufficient cells from patients NL, HA, CAD24D for receptor analyses.

F3-150

CAD25 and CAD were CD34⁺ cells.

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