Table 1. Clinical Characteristics of AML... | American Society of Hematology

Table 1.

Clinical Characteristics of AML Patients and Growth of Cells in Control Cultures

Patient No.	FAB	WBC × 10⁹/L	% Blasts	Cytogenetic Change	% CD34	CFU^*/10⁵	CFU in SC wk 4^†/10⁵	CFU in SC wk 8/10⁵
1	M1	100	90	Normal	0.1	12	15	57
2	M5	155	39	t(9;11)	1.1	88	80	806
3	M5	47	23	del 11q23	48	870	6	13
4	M4	370	46	+13	28	300	17,728	51
5	M4	71	76	+8	76	910	10	57
6	M5	430	98	ND	2	5	5	0
7	M4	103	42	del 16q	3	13	2	0
8	M5	50	92	+8,+8, t(9;11)	0.4	1,060	3,413	0
9	M4e	130	70	inv 16	10	3	178	0
10	M4e	65	80	inv 16	87	6	133	7
11	M4e	19	34	inv 16	48	10	3	6
12	M4e	18	52	inv 16	78	18	11	96
13	M2	57	51	+8, t(12;22), del 20q	11	182	928	256
14	M2	29	38	t(6;9)	1.6	800	995	2,161
15	M5	94	73	Normal	0.1	148	204	882
16	M4	87	73	del 16q22	4	116	4	14
17	M1	27	80	t(8;20)	7	ND	ND	ND
18	M5	94	73	+8	0.5	2	2	14
19	M5b	12	23	Normal	3	9	2	21

Patient No.	FAB	WBC × 10⁹/L	% Blasts	Cytogenetic Change	% CD34	CFU^*/10⁵	CFU in SC wk 4^†/10⁵	CFU in SC wk 8/10⁵
1	M1	100	90	Normal	0.1	12	15	57
2	M5	155	39	t(9;11)	1.1	88	80	806
3	M5	47	23	del 11q23	48	870	6	13
4	M4	370	46	+13	28	300	17,728	51
5	M4	71	76	+8	76	910	10	57
6	M5	430	98	ND	2	5	5	0
7	M4	103	42	del 16q	3	13	2	0
8	M5	50	92	+8,+8, t(9;11)	0.4	1,060	3,413	0
9	M4e	130	70	inv 16	10	3	178	0
10	M4e	65	80	inv 16	87	6	133	7
11	M4e	19	34	inv 16	48	10	3	6
12	M4e	18	52	inv 16	78	18	11	96
13	M2	57	51	+8, t(12;22), del 20q	11	182	928	256
14	M2	29	38	t(6;9)	1.6	800	995	2,161
15	M5	94	73	Normal	0.1	148	204	882
16	M4	87	73	del 16q22	4	116	4	14
17	M1	27	80	t(8;20)	7	ND	ND	ND
18	M5	94	73	+8	0.5	2	2	14
19	M5b	12	23	Normal	3	9	2	21

Abbreviations: ND, not determined; wbc, white blood cells.

CFU, leukemic clusters (10 to 20 cells) plus colonies (>20 cells) scored after 14 days in methylcellulose culture per 10⁵cells plated.

CFU in SC wk4, CFU in 4-week-old suspension cultures initiated with 10⁵ cells. CFU numbers were corrected for weekly depopulation.