Table 1.

Reports and Our Data of MDR1/P-gp Expression and Clinical Course of AML Patients

Investigators Year and ReferencesMethods Samples CR Rate (%)
MDR1/P-gp Positive MDR1/P-gp Negative
Kuwazuru et al  1990 (14)  Western blot  19 1/10 (10%)  7/9 (77%)  
Marie et al  1991 (15) Northern blot  29  7/21 (30%)  5/8 (63%)  
Campos et al  1992 (16)  FACS  150  23/71 (32%)  64/79 (81%) 
Nüssler et al  1996 (17)  FACS  166 26/88 (29%)  93/141 (66%)  
Nakayama et al  This study Quantitative RT-PCR  34  7/21 (33%) 8/13 (62%) 
Investigators Year and ReferencesMethods Samples CR Rate (%)
MDR1/P-gp Positive MDR1/P-gp Negative
Kuwazuru et al  1990 (14)  Western blot  19 1/10 (10%)  7/9 (77%)  
Marie et al  1991 (15) Northern blot  29  7/21 (30%)  5/8 (63%)  
Campos et al  1992 (16)  FACS  150  23/71 (32%)  64/79 (81%) 
Nüssler et al  1996 (17)  FACS  166 26/88 (29%)  93/141 (66%)  
Nakayama et al  This study Quantitative RT-PCR  34  7/21 (33%) 8/13 (62%) 

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