Table 1. Hematological and Biochemical... | American Society of Hematology

Table 1.

Hematological and Biochemical Data

Patient	Age (yr)	Hb (g/dL)	Reticulocyte Counts (μL)	DI_iso	Sp:Band 3 Ratio	% of SpD in 4°C Extracts	% of Spα^I/74 Variant	% of Spα^V/41 Peptide
Father	25	14.8	84,800	0.20	0.96	54.2	43.2
Mother	29	12.1	65,450	0.12	1.04	40.2	45	4.7
Proband	1	8.3	243,500	0.12	0.97	45.8	56.5	1.5
Normal values				0.38 to 0.52	0.98 ± 0.06 (n = 40)	21.1 ± 1.8 (n = 7)		2.3 ± 0.4 (n = 10)^*
								4.1 ± 1.6 (n = 4)^†

Patient	Age (yr)	Hb (g/dL)	Reticulocyte Counts (μL)	DI_iso	Sp:Band 3 Ratio	% of SpD in 4°C Extracts	% of Spα^I/74 Variant	% of Spα^V/41 Peptide
Father	25	14.8	84,800	0.20	0.96	54.2	43.2
Mother	29	12.1	65,450	0.12	1.04	40.2	45	4.7
Proband	1	8.3	243,500	0.12	0.97	45.8	56.5	1.5
Normal values				0.38 to 0.52	0.98 ± 0.06 (n = 40)	21.1 ± 1.8 (n = 7)		2.3 ± 0.4 (n = 10)^*
								4.1 ± 1.6 (n = 4)^†

DI_iso, deformability index in isotonicity (osmotic gradient ektacytometry studies).

Values observed in normal control subjects heterozygous for the Spα^Lely allele.

Values observed in normal control subjects homozygous for the Spα^Lely allele.