Table 1.

No Inhibition of Colony Formation of Normal Bone Marrow Progenitor Cells by Treatment With the Anti-TNF Ribozyme Rzd

Added Compound No. of Colonies
G GM M Total
Ribozyme Rzd  8 ± 3 29 ± 5  34 ± 4  71 ± 5  
Only liposome (DOTAP) 9 ± 4  31 ± 4  32 ± 3  71 ± 4  
None 8 ± 4  28 ± 6  32 ± 7  68 ± 8 
Added Compound No. of Colonies
G GM M Total
Ribozyme Rzd  8 ± 3 29 ± 5  34 ± 4  71 ± 5  
Only liposome (DOTAP) 9 ± 4  31 ± 4  32 ± 3  71 ± 4  
None 8 ± 4  28 ± 6  32 ± 7  68 ± 8 

Values are means ± SEM based on triplicate measurements from the healthy child.

Abbreviations: G, neutrophilic granulocyte; GM, neutrophilic granulocyte-monocyte; M, monocyte-macrophage.

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