No Inhibition of Colony Formation of Normal Bone Marrow Progenitor Cells by Treatment With the Anti-TNF Ribozyme Rzd
Added Compound . | No. of Colonies . | |||
---|---|---|---|---|
G . | GM . | M . | Total . | |
Ribozyme Rzd | 8 ± 3 | 29 ± 5 | 34 ± 4 | 71 ± 5 |
Only liposome (DOTAP) | 9 ± 4 | 31 ± 4 | 32 ± 3 | 71 ± 4 |
None | 8 ± 4 | 28 ± 6 | 32 ± 7 | 68 ± 8 |
Added Compound . | No. of Colonies . | |||
---|---|---|---|---|
G . | GM . | M . | Total . | |
Ribozyme Rzd | 8 ± 3 | 29 ± 5 | 34 ± 4 | 71 ± 5 |
Only liposome (DOTAP) | 9 ± 4 | 31 ± 4 | 32 ± 3 | 71 ± 4 |
None | 8 ± 4 | 28 ± 6 | 32 ± 7 | 68 ± 8 |
Values are means ± SEM based on triplicate measurements from the healthy child.
Abbreviations: G, neutrophilic granulocyte; GM, neutrophilic granulocyte-monocyte; M, monocyte-macrophage.