Neutralization of Primary HIV Isolates by Plasma From LTS and Progressors
| Plasma . | Titer . | Virus Isolates . | ||
|---|---|---|---|---|
| Autologous . | Heterologous (LTS)* . | Heterologous (Progressors)* . | ||
| LTS | 0 | 2/7 (29)6-151 | 2/11 (18) | 7/25 (28) |
| 10 | 2/7 (29) | 7/11 (64) | 15/25 (60) | |
| 50 | 1/7 (14) | 1/11 (9) | 3/25 (12) | |
| 100 | 2/7 (29) | 1/11 (9) | 0/25 (0) | |
| Progressors | 0 | 1/6 (17) | 11/25 (44) | 7/23 (30) |
| 10 | 5/6 (83) | 12/25 (48) | 13/23 (57) | |
| 50 | 0/6 (0) | 5/25 (20) | 3/23 (13) | |
| 100 | 0/6 (0) | 0/25 (0) | 0/23 (0) | |
| Plasma . | Titer . | Virus Isolates . | ||
|---|---|---|---|---|
| Autologous . | Heterologous (LTS)* . | Heterologous (Progressors)* . | ||
| LTS | 0 | 2/7 (29)6-151 | 2/11 (18) | 7/25 (28) |
| 10 | 2/7 (29) | 7/11 (64) | 15/25 (60) | |
| 50 | 1/7 (14) | 1/11 (9) | 3/25 (12) | |
| 100 | 2/7 (29) | 1/11 (9) | 0/25 (0) | |
| Progressors | 0 | 1/6 (17) | 11/25 (44) | 7/23 (30) |
| 10 | 5/6 (83) | 12/25 (48) | 13/23 (57) | |
| 50 | 0/6 (0) | 5/25 (20) | 3/23 (13) | |
| 100 | 0/6 (0) | 0/25 (0) | 0/23 (0) | |
*Plasma from HIV-infected subjects was tested against one or more heterologous virus isolates.
The number of plasma samples which neutralized the HIV isolates was determined by comparison with the effect on virus replication by a plasma pool from control HIV seronegative donors. Number in parentheses indicates the percentage of plasma samples which neutralized the virus isolates by at least 66%.