EPO mRNA Expression in Renal Tissue at Different Stages of Gestation
| Age . | ≤30 wk of Gestation . | 31 to 40 wk of Gestation . | ≥41 wk of Gestation, Infants . | P Value . |
|---|---|---|---|---|
| EPO mRNA positive samples | 43 of 46 | 7 of 9 | 5 of 5 | |
| No./% | 93% | 77% | 100% | |
| Weight (g) | 1.80 (0.37-7.30) | 7.60 (5.85-17.40) | 16.10 (11.00-30.50) | I: <.001 II: NS |
| Total RNA/g | 1.000 (71-2.100) | 1,086 (443-2.386) | 1.786 (625-6.045) | I: NS II: NS |
| EPO mRNA (amol/μg total RNA) | 0.58 (0.12-7.31) | 1.86 (0.35-5.80) | 14.50 (0.12-730.80) | I: <.05 II: NS |
| EPO mRNA (amol/g) | 592 (14-11,797) | 1,936 (244-13,841) | 12,272 (131-1,305,000) | I: <.05 II: NS |
| Total EPO mRNA (amol/organ) | 915 (10-57,806) | 15,710 (1851-240,832) | 276,406 (2,108-23,490,000) | I: <.001 II: NS |
| Age . | ≤30 wk of Gestation . | 31 to 40 wk of Gestation . | ≥41 wk of Gestation, Infants . | P Value . |
|---|---|---|---|---|
| EPO mRNA positive samples | 43 of 46 | 7 of 9 | 5 of 5 | |
| No./% | 93% | 77% | 100% | |
| Weight (g) | 1.80 (0.37-7.30) | 7.60 (5.85-17.40) | 16.10 (11.00-30.50) | I: <.001 II: NS |
| Total RNA/g | 1.000 (71-2.100) | 1,086 (443-2.386) | 1.786 (625-6.045) | I: NS II: NS |
| EPO mRNA (amol/μg total RNA) | 0.58 (0.12-7.31) | 1.86 (0.35-5.80) | 14.50 (0.12-730.80) | I: <.05 II: NS |
| EPO mRNA (amol/g) | 592 (14-11,797) | 1,936 (244-13,841) | 12,272 (131-1,305,000) | I: <.05 II: NS |
| Total EPO mRNA (amol/organ) | 915 (10-57,806) | 15,710 (1851-240,832) | 276,406 (2,108-23,490,000) | I: <.001 II: NS |
(Median and range). I: ≤30 v 31 to 40 weeks of gestation; II: 31 to 40 v ≥41 weeks.
Abbreviation: NS, not significant.