Table 2.

Initial Patient Characteristics of the Two Study Populations

All Patients AIEOP BFM P Value
61  23  38  
Male (%)  66  61  68  .58* 
Age  
 Median (yr)  7.5  7.4  7.7  .72 
 Min/max (yr)   1.2/16.6   1.2/14.9  2.2/16.6  
WBC  
 Median (×106/L) 75,000  150,000  73,550  .13 
 Min/max (×106/L)   2,200/572,200    5,400/572,200    2,200/410,000 
BFM RF (median) 1.24  1.33  1.22  .82 
Immunophenotype1-153 
 Common (%)  77  70  82  .35* 
 Pre-B (%)  16  22  13  .48* 
 T (%)  5  5  1.0* 
≥1 My marker1-155 (%)  29  37  25  .51* 
PPR¶ (%)  35  38  33  .78* 
All Patients AIEOP BFM P Value
61  23  38  
Male (%)  66  61  68  .58* 
Age  
 Median (yr)  7.5  7.4  7.7  .72 
 Min/max (yr)   1.2/16.6   1.2/14.9  2.2/16.6  
WBC  
 Median (×106/L) 75,000  150,000  73,550  .13 
 Min/max (×106/L)   2,200/572,200    5,400/572,200    2,200/410,000 
BFM RF (median) 1.24  1.33  1.22  .82 
Immunophenotype1-153 
 Common (%)  77  70  82  .35* 
 Pre-B (%)  16  22  13  .48* 
 T (%)  5  5  1.0* 
≥1 My marker1-155 (%)  29  37  25  .51* 
PPR¶ (%)  35  38  33  .78* 

*Fisher exact test.

Wilcoxon test.

The BFM RF was not available from 1 patient.

F1-153

Only 1 patient was diagnosed with pre-pre-B ALL.

F1-155

Data available from 52 patients.

¶Data for prednisone response available from 57 patients.

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