Table 1. Clinical and Histologic... | American Society of Hematology

Table 1.

Clinical and Histologic Parameters in Retreated Patients

	Patients With Cryoglobulins (previous IFN relapsers)	Patient Without Cryoglobulins (previous IFN relapsers)
End of therapy response (ALT and HCV-RNA)	11/13^-150 (84.6%)	11/14^† (78.6%)
Sustained response (1 yr after therapy) (ALT and HCV-RNA)	5/13 (38.5%)	5/14 (35.7%)
Mean ALT
Pre	168 ± 65^-150	149 ± 58^†
End of therapy	65 ± 70^-150	61 ± 59^†
Post	134 ± 84	128 ± 79
Cryocrit
Pre	1.41 ± 0.9^-150,^-152	—
End of therapy	0.38 ± 0.6^-150	—
Post	0.64 ± 0.6^-152	—
Histological scores
HAI
Pre	6.9 ± 2.1	7.8 ± 3.9
Post	5.6 ± 2.2	5.9 ± 2.4
Fibrosis
Pre	1.9 ± 0.9	2.1 ± 0.9
Post	1.7 ± 0.7	1.8 ± 0.6

	Patients With Cryoglobulins (previous IFN relapsers)	Patient Without Cryoglobulins (previous IFN relapsers)
End of therapy response (ALT and HCV-RNA)	11/13^-150 (84.6%)	11/14^† (78.6%)
Sustained response (1 yr after therapy) (ALT and HCV-RNA)	5/13 (38.5%)	5/14 (35.7%)
Mean ALT
Pre	168 ± 65^-150	149 ± 58^†
End of therapy	65 ± 70^-150	61 ± 59^†
Post	134 ± 84	128 ± 79
Cryocrit
Pre	1.41 ± 0.9^-150,^-152	—
End of therapy	0.38 ± 0.6^-150	—
Post	0.64 ± 0.6^-152	—
Histological scores
HAI
Pre	6.9 ± 2.1	7.8 ± 3.9
Post	5.6 ± 2.2	5.9 ± 2.4
Fibrosis
Pre	1.9 ± 0.9	2.1 ± 0.9
Post	1.7 ± 0.7	1.8 ± 0.6

Abbreviation: Post, 12 months after therapy.

and † P < .001.

P < .05.